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用于生物医学应用的仿生微结构纤维。

Bioinspired micro-structured fibers for biomedical applications.

作者信息

Guo Jiahui, Miao Shuangshuang, Sun Lingyu, Zhao Yuanjin, Gu Xiaosong

机构信息

Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China.

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.

出版信息

Bioact Mater. 2025 Jul 14;53:218-239. doi: 10.1016/j.bioactmat.2025.07.012. eCollection 2025 Nov.

Abstract

Fibers, which are common in nature, have been playing an integral role in the life of mankind ranging from traditional textile industries to modern medical fields. Inspired by the spinning process of spider/silkworm, impressive advancements have been achieved in the design and development of bioinspired fiber materials with diverse microstructures. In this review, we provide an overall summarization into the latest progress in the structures and applications of bioinspired fibers. Following an introduction to natural fiber systems (e.g., spider silk, silkworm silk, and muscle structures), we focus on the fabrication methods and characterization techniques for the preparation of bioinspired fibers with tailored structures. Emphasis is also given to the summarization of their biomedical applications. Furthermore, some insights into the challenges and even opportunities that need to be faced in the future development process are given.

摘要

纤维在自然界中很常见,从传统纺织工业到现代医学领域,它在人类生活中一直发挥着不可或缺的作用。受蜘蛛/蚕的纺丝过程启发,在具有多样微观结构的仿生纤维材料的设计与开发方面取得了令人瞩目的进展。在这篇综述中,我们对仿生纤维的结构和应用的最新进展进行了全面总结。在介绍天然纤维系统(如蜘蛛丝、蚕丝和肌肉结构)之后,我们重点关注制备具有定制结构的仿生纤维的制造方法和表征技术。同时也着重总结了它们的生物医学应用。此外,还对未来发展过程中需要面对的挑战乃至机遇给出了一些见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e444/12281455/d2c6892a83f7/ga1.jpg

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