下一代计算肿瘤模型面临的挑战与机遇。
Challenges and opportunities for the next generation of computational tumor models.
作者信息
Munn Lance L, Jain Rakesh K
机构信息
Edwin L Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
出版信息
PLoS Biol. 2025 Jul 23;23(7):e3003269. doi: 10.1371/journal.pbio.3003269. eCollection 2025 Jul.
Abstract
Mathematical models have become essential tools for exploring the complex interplay between cancer cells and their microenvironment, but require multidisciplinary expertise and abundant biological data to develop. AI is leading the way towards the next wave of tumor models.
摘要
数学模型已成为探索癌细胞与其微环境之间复杂相互作用的重要工具，但开发此类模型需要多学科专业知识和丰富的生物学数据。人工智能正引领着下一波肿瘤模型的发展方向。
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