Mirković Snježana, Martinović Milica, Tadić Vanja M, Nešić Ivana, Jovanović Aleksandra Stolić, Žugić Ana
PHI Hospital "Sveti Vračevi", Srpske vojske 53, 76300 Bijeljina, Bosnia and Herzegovina.
Department of Pharmacy, Faculty of Medicine, University of Nis, Boulevard Dr. Zorana Djindjića 81, 18000 Nis, Serbia.
Antibiotics (Basel). 2025 Jul 3;14(7):677. doi: 10.3390/antibiotics14070677.
Essential oils are lipophilic secondary metabolites produced in various parts of aromatic plants and stored in specialized secretory structures. They play a vital role in plant defense, offering protection against microorganisms and herbivores. These oils are known for a wide range of biological activities, including antibacterial, anti-inflammatory, antitumor, analgesic, antioxidant, and immunomodulatory effects. Given the increasing interest in natural alternatives to synthetic drugs, this review explored the therapeutic relevance of -derived essential oils as promising candidates in modern phytotherapy. Species of the genus have been widely investigated for their phytochemical composition and biological potential, with a focus on their medicinal and pharmaceutical applications. This review aimed to assess the biological properties of species commonly used in traditional medicine. In this paper, thorough insight into the chemical composition, as well as into the antimicrobial and antioxidant activities of essential oils obtained from the different parts of species, was given. Although recognized for their antimicrobial activity against a wide range of bacterial strains, including both Gram-positive and Gram-negative bacteria, the practical application of essential oils is often limited by their physicochemical instability and volatility. Therefore, this review highlighted the advances in formulation strategies, particularly encapsulation techniques, as the possible direction of future research concerning essential oils.
精油是在芳香植物的各个部位产生并储存在专门分泌结构中的亲脂性次生代谢产物。它们在植物防御中起着至关重要的作用,能抵御微生物和食草动物。这些精油以其广泛的生物活性而闻名,包括抗菌、抗炎、抗肿瘤、镇痛、抗氧化和免疫调节作用。鉴于对合成药物天然替代品的兴趣日益增加,本综述探讨了源自[具体植物属名]的精油作为现代植物疗法中有前景候选物的治疗相关性。[具体植物属名]属的物种因其植物化学成分和生物潜力而受到广泛研究,重点是它们的药用和制药应用。本综述旨在评估传统医学中常用的[具体植物属名]物种的生物学特性。本文深入探讨了从[具体植物属名]物种不同部位获得的精油的化学成分以及抗菌和抗氧化活性。尽管[具体植物属名]精油对包括革兰氏阳性菌和革兰氏阴性菌在内的多种细菌菌株具有抗菌活性,但其实际应用往往受到其物理化学不稳定性和挥发性的限制。因此,本综述强调了制剂策略的进展,特别是包封技术,作为未来关于精油研究的可能方向。