Zarrelli Armando
Department of Chemical Sciences, University of Naples Federico II, Via Vicinale Cupa Cintia 26, 80126 Naples, Italy.
Molecules. 2025 Jul 11;30(14):2935. doi: 10.3390/molecules30142935.
The aim of this study was to elucidate all the degradation byproducts (DBPs) of bemotrizinol (BEMT) that are associated with sodium hypochlorite treatment. BEMT is a UV filter that is found not only in many personal care products, such as sunscreen and cosmetics, but also as an additive in plastics or clothing to protect them from damage that results from absorbed radiation. BEMT has been detected in wastewater, surface water, and some lake sediments, in quantities from a few ng/L to hundreds of ng/L, to such an extent that, today, it is considered an emerging pollutant. In this study, the UV filter was subjected to oxidation with sodium hypochlorite, which is an oxidant at the base of the disinfection process that is used in most wastewater treatment plants or in swimming pools. Using different chromatographic methods (CC, TLC, HPLC, and GC), the resulting DBP mixture was separated into its main components, which were then identified using one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. Nineteen DBPs were isolated, and a plausible reaction mechanism was proposed to explain how they were obtained.
本研究的目的是阐明与次氯酸钠处理相关的倍他米松（BEMT）的所有降解副产物（DBP）。BEMT是一种紫外线过滤剂，不仅存在于许多个人护理产品中，如防晒霜和化妆品，还作为塑料或衣物中的添加剂，以保护它们免受吸收辐射造成的损害。在废水、地表水和一些湖泊沉积物中已检测到BEMT，含量从几纳克/升到数百纳克/升不等，以至于如今它被视为一种新兴污染物。在本研究中，这种紫外线过滤剂用次氯酸钠进行氧化处理，次氯酸钠是大多数污水处理厂或游泳池消毒过程中使用的一种氧化剂。使用不同的色谱方法（柱色谱、薄层色谱、高效液相色谱和气相色谱），将所得的DBP混合物分离成其主要成分，然后使用一维和二维核磁共振（NMR）光谱以及质谱对其进行鉴定。分离出了19种DBP，并提出了一个合理的反应机理来解释它们是如何形成的。
