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LGD_Net:用于使用CT扫描对肺部疾病进行分类的带极限学习机的胶囊网络。

LGD_Net: Capsule network with extreme learning machine for classification of lung diseases using CT scans.

作者信息

Khan Ali Haider, Li Jianqiang, Asghar Muhammad Nabeel, Iqbal Sajid

机构信息

College of Computer Science, Beijing University of Technology, Beijing, China.

Department of Information Systems, College of Computer Sciences and Information Technology, King Faisal University, Al Hofuf, Saudi Arabia.

出版信息

PLoS One. 2025 Aug 8;20(8):e0327419. doi: 10.1371/journal.pone.0327419. eCollection 2025.

DOI:10.1371/journal.pone.0327419
PMID:40779565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12334061/
Abstract

Lung diseases (LGDs) are related to an extensive range of lung disorders, including pneumonia (PNEUM), lung cancer (LC), tuberculosis (TB), and COVID-19 etc. The diagnosis of LGDs is performed by using different medical imaging such as X-rays, CT scans, and MRI. However, LGDs contain similar symptoms such as fever, cough, and sore throat, making it challenging for radiologists to classify these LGDs. If LGDs are not diagnosed at their initial phase, they may produce severe complications or even death. An automated classifier is required for the classification of LGDs. Thus, this study aims to propose a novel model named lung diseases classification network (LGD_Net) based on the combination of a capsule network (CapsNet) with the extreme learning machine (ELM) for the classification of five different LGDs such as PNEUM, LC, TB, COVID-19 omicron (COO), and normal (NOR) using CT scans. The LGD_Net model is trained and tested on the five publicly available benchmark datasets. The datasets contain an imbalanced distribution of images; therefore, a borderline SMOTE (BL_SMT) approach is applied to handle this problem. Additionally, the affine transformation methods are used to enhance LGD datasets. The performance of the LGD_Net is compared with four CNN-based baseline models such as Vgg-19 (D1), ResNet-101 (D2), Inception-v3 (D3), and DenseNet-169 (D4). The LGD_Net model achieves an accuracy of 99.71% in classifying LGDs using CT scans. While the other models such as D1, D2, D3, and D4 attains an accuracy of 91.21%, 94.39%, 93.96%, and 93.82%, respectively. The findings demonstrate that the LGD_Net model works significantly as compared to D1, D2, D3, and D4 as well as state-of-the-art (SOTA). Thus, this study concludes that the LGD_Net model provides significant assistance to radiologists in classifying several LGDs.

摘要

肺部疾病(LGDs)与多种肺部疾病相关,包括肺炎(PNEUM)、肺癌(LC)、肺结核(TB)和新冠肺炎(COVID-19)等。LGDs的诊断通过使用不同的医学成像手段进行,如X射线、CT扫描和MRI。然而,LGDs具有相似的症状,如发热、咳嗽和喉咙痛,这使得放射科医生对这些LGDs进行分类具有挑战性。如果LGDs在初始阶段未被诊断出来,可能会产生严重的并发症甚至死亡。因此,需要一个自动分类器来对LGDs进行分类。因此,本研究旨在提出一种名为肺部疾病分类网络(LGD_Net)的新型模型,该模型基于胶囊网络(CapsNet)与极限学习机(ELM)的结合,用于使用CT扫描对肺炎、肺癌、肺结核、新冠肺炎奥密克戎变异株(COO)和正常(NOR)这五种不同的LGDs进行分类。LGD_Net模型在五个公开可用的基准数据集上进行了训练和测试。这些数据集包含图像分布不均衡的问题;因此,应用了边界合成少数类过采样技术(BL_SMT)来处理这个问题。此外,仿射变换方法被用于增强LGD数据集。将LGD_Net的性能与四个基于卷积神经网络(CNN)的基线模型进行了比较,如Vgg-19(D1)、ResNet-101(D2)、Inception-v3(D3)和DenseNet-169(D4)。LGD_Net模型在使用CT扫描对LGDs进行分类时达到了99.71%的准确率。而其他模型,如D1、D2、D3和D4的准确率分别为91.21%、94.39%、93.96%和93.82%。研究结果表明,与D1、D2、D3、D4以及现有技术(SOTA)相比,LGD_Net模型的效果显著。因此,本研究得出结论,LGD_Net模型在对多种LGDs进行分类时为放射科医生提供了重要帮助。

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