Alimohammadi Iraj, Rafieepour Athena, Ashtarinezhad Azadeh, Hosseini Agha Fatemeh, Tabatabaei Seyed Hosein, Jafari Hossein, Asadi Raziyeh
Occupational Health Research Center, Department of Occupational Health, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Health Promotion Research Center, Department of Occupational Health, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Sci Rep. 2025 Aug 19;15(1):30280. doi: 10.1038/s41598-025-16023-3.
Noise is recognized as a psychological stressor that led to noise annoyance, and individual noise sensitivity could play a moderating role. This study aimed to investigate the association between noise annoyance, noise sensitivity, and oxidative stress responses among workers in metal manufacturing industries. A total of 161 workers participated in the study. Demographic data and noise sensitivity were assessed using the Weinstein Noise Sensitivity Scale, while noise annoyance was evaluated via the ISO/TS 15666:2003 questionnaire. Daily noise exposure was measured using a sound level meter. Serum levels of oxidative stress biomarkers, including Malondialdehyde (MDA), Total Antioxidant Capacity (TAC), and 8-hydroxy-2'-deoxyguanosine (8-OHdG), were determined using ZellBio diagnostic kits. Statistical analyses were performed in SPSS v.18, with a significance threshold of 0.05. The mean equivalent noise level was 80.11 ± 11.3 dBA. Among participants, 80.1% reported some degree of noise annoyance, and 74% reported noise sensitivity. No significant association was observed between demographic variables and oxidative stress markers, nor between noise sensitivity or annoyance and induction of oxidative stress. These findings suggest that, under current exposure conditions, subjective reactions to noise, such as annoyance and sensitivity, may not significantly influence oxidative stress, highlighting the need for further investigation into other modulating factors.
噪声被认为是一种导致噪声烦恼的心理应激源，个体噪声敏感性可能起调节作用。本研究旨在调查金属制造业工人的噪声烦恼、噪声敏感性与氧化应激反应之间的关联。共有161名工人参与了该研究。使用温斯坦噪声敏感性量表评估人口统计学数据和噪声敏感性，同时通过ISO/TS 15666:2003问卷评估噪声烦恼。使用声级计测量每日噪声暴露。使用ZellBio诊断试剂盒测定氧化应激生物标志物的血清水平，包括丙二醛（MDA）、总抗氧化能力（TAC）和8-羟基-2'-脱氧鸟苷（8-OHdG）。在SPSS v.18中进行统计分析，显著性阈值为0.05。平均等效噪声水平为80.11±11.3 dBA。在参与者中，80.1%报告有一定程度的噪声烦恼，74%报告有噪声敏感性。在人口统计学变量与氧化应激标志物之间，以及噪声敏感性或烦恼与氧化应激诱导之间均未观察到显著关联。这些发现表明，在当前暴露条件下，对噪声的主观反应，如烦恼和敏感性，可能不会显著影响氧化应激，这突出了对其他调节因素进行进一步研究的必要性。
