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埃塞俄比亚的风湿性心脏病与避孕措施使用情况:一项横断面研究

Rheumatic Heart Disease and Contraception Use in Ethiopia: A Cross-Sectional Study.

作者信息

Zewde Samrawit A, Weldehana Amha M, Zewde Daniel A, Ayele Zelalem B, Abebe Shiferaw N

机构信息

Obstetrics and Gynecology, College of Health Science, Addis Ababa University, Addis Ababa, ETH.

Internal Medicine, College of Health Science, Addis Ababa University, Addis Ababa, ETH.

出版信息

Cureus. 2025 Jul 22;17(7):e88541. doi: 10.7759/cureus.88541. eCollection 2025 Jul.

Abstract

Background Women of reproductive age with rheumatic heart disease (RHD) face a high risk of cardiovascular complications during pregnancy. Consequently, preconception counseling and contraception are routinely recommended for all women of reproductive age. In Ethiopia, there are no data available regarding contraception coverage among women with RHD. Objectives The aims of this study were to examine the prevalence of contraceptive use, investigate the most common methods, and identify factors influencing contraception use among reproductive-age women with RHD in Ethiopia. Methodology The study included patients who were followed at a tertiary hospital between January 1, 2017, and October 30, 2018. A total of 359 women aged 15 to 49 years with RHD were randomly selected and evaluated using standardized questionnaires and chart reviews. Chi-square and logistic regression analyses were utilized to measure associations. A p-value of ≤0.05 was deemed significant, with a 95% confidence interval. Results The mean age was 30.96 ±7.84 years. Of the patients, 219 (61%) were unemployed, and only 92 (25%) had higher education. Of the 241 (67%) who had severe RHD, 205 (57%) had combined valve lesions, 76 (21.2%) had isolated mitral stenosis, and 62 (17.3%) had isolated mitral regurgitation. Of the total of 359 patients, 300 (83.6%) had symptoms; 241 (67.1%) were class IV per the modified World Health Organization (mWHO) cardiovascular risk assessment, and the rest, 118 (32.9%), were class III. A total of 139 (38.9%) and 112 (31.3%) were on warfarin and angiotensin-converting enzyme inhibitors, respectively. However, only 149 (41.5%) were on contraceptives, and among non-users, 226 (63%) reported no counseling. Injectables were the most used contraceptive, followed by intrauterine devices and oral pills. Marital status (OR: 3.26, 95% CI: 2.03-5.22, P < 0.001) and employment (OR: 3.82, 95% CI: 1.58-9.24, P = 0.003) were the only two statistically significant factors associated with contraception use. Conclusion Contraception use was low among women with RHD in Ethiopia. Patients with contraindications for pregnancy were not provided with adequate counseling and contraception. Additionally, those who were using contraception were on ineffective methods. Further action is needed to improve contraception use among women with RHD.

摘要

背景

患有风湿性心脏病(RHD)的育龄妇女在怀孕期间面临心血管并发症的高风险。因此,常规建议所有育龄妇女进行孕前咨询和避孕。在埃塞俄比亚,尚无关于患有RHD的妇女避孕覆盖率的数据。

目的

本研究的目的是调查埃塞俄比亚患有RHD的育龄妇女的避孕使用率,调查最常用的方法,并确定影响避孕使用的因素。

方法

该研究纳入了2017年1月1日至2018年10月30日在一家三级医院接受随访的患者。总共随机选择了359名年龄在15至49岁之间患有RHD的妇女,并使用标准化问卷和病历审查进行评估。采用卡方检验和逻辑回归分析来衡量相关性。p值≤0.05被认为具有统计学意义,置信区间为95%。

结果

平均年龄为30.96±7.84岁。在这些患者中,219名(61%)失业,只有92名(25%)接受过高等教育。在241名(67%)患有严重RHD的患者中,205名(57%)患有联合瓣膜病变,76名(21.2%)患有单纯二尖瓣狭窄,62名(17.3%)患有单纯二尖瓣反流。在总共359名患者中,300名(83.6%)有症状;根据改良世界卫生组织(mWHO)心血管风险评估,241名(67.1%)为IV级,其余118名(32.9%)为III级。分别有139名(38.9%)和112名(31.3%)正在服用华法林和血管紧张素转换酶抑制剂。然而,只有149名(41.5%)正在使用避孕药具,在未使用者中,226名(63%)报告未接受咨询。注射剂是最常用的避孕方法,其次是宫内节育器和口服避孕药。婚姻状况(OR:3.26,95%CI:2.03 - 5.22,P < 0.001)和就业情况(OR:3.82,95%CI:1.58 - 9.24,P = 0.003)是与避孕使用相关的仅有的两个具有统计学意义的因素。

结论

埃塞俄比亚患有RHD的妇女避孕使用率较低。有妊娠禁忌症的患者未得到充分的咨询和避孕措施。此外,那些正在使用避孕措施的人采用的是无效方法。需要采取进一步行动来提高患有RHD的妇女的避孕使用率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c4e/12370237/3ab67e2f102f/cureus-0017-00000088541-i01.jpg

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