Enterline P E, Viren J
Environ Health Perspect. 1985 Oct;62:303-12. doi: 10.1289/ehp.8562303.
A recent animal experiment suggests that gasoline exposure may be a cause of human kidney cancer. This is a literature review to see whether there is any epidemiologic support for these animal findings. Trends and geographic patterns in gasoline consumption and kidney cancer mortality are moderately supportive of a relationship, although this cannot be considered important evidence for a causal relationship. Most other ecological correlations are not supportive of a relationship. Eleven oil refinery populations and one population of petroleum products distribution workers have been studied. These studies taken as a group do not appear to support the notion of a relationship between gasoline exposure and kidney cancer. However, most were not designed or analyzed with this hypothesis in mind. An examination of these data which attempts to consider the ages of the populations studied provides some evidence of a small kidney cancer excess among older workers or among workers exposed for long periods. Because of the importance of gasoline and the potential for exposure by the public further study of exposed populations is needed.
最近的一项动物实验表明，接触汽油可能是人类肾癌的一个病因。这是一篇文献综述，旨在查看是否有任何流行病学证据支持这些动物实验结果。汽油消费和肾癌死亡率的趋势及地理模式适度支持两者之间存在关联，尽管这不能被视为因果关系的重要证据。大多数其他生态相关性并不支持这种关联。已对11个炼油厂人群和1个石油产品分销工人人群进行了研究。总体来看，这些研究似乎并不支持接触汽油与肾癌之间存在关联的观点。然而，大多数研究在设计或分析时并未考虑这一假设。对这些数据进行的一项考虑所研究人群年龄的分析，为老年工人或长期接触汽油的工人中肾癌略有增加提供了一些证据。鉴于汽油的重要性以及公众接触汽油的可能性，需要对接触人群进行进一步研究。
