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针对人类B淋巴母细胞的膜抗原证据。

Evidence for membrane antigen(s) specific for human B lymphoblasts.

作者信息

Thomas D B, Phillips B

出版信息

Clin Exp Immunol. 1973 May;14(1):91-6.

Abstract

IgM antibodies against surface antigen(s) of a subpopulation of PHA-induced lymphoblasts have been found in the sera (20%) of infectious mononucleosis patients by indirect immunofluorescent staining. Maximum staining was obtained at 3°C. Evidence is presented that this subpopulation is derived from B lymphocytes. Common antigenic determinants were also present on four human lymphoid cell lines.

摘要

通过间接免疫荧光染色法,在传染性单核细胞增多症患者的血清(20%)中发现了针对PHA诱导的淋巴母细胞亚群表面抗原的IgM抗体。在3°C时获得最大染色效果。有证据表明该亚群源自B淋巴细胞。在四种人类淋巴细胞系上也存在共同的抗原决定簇。

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