Burge P S, Harries M G, O'Brien I M, Pepys J
Clin Allergy. 1978 Jan;8(1):1-14. doi: 10.1111/j.1365-2222.1978.tb00441.x.
Twenty-one patients are described who developed asthma, or evidence of a peripheral airways reaction, while working in the electronics industry and exposed to solder flux fumes containing colophony (pine resin). This selected group contained five patients with pre-existing asthma. Fourteen patients had never smoked. Prick-testing with common environmental antigens gave one or more positive reactions in nine patients. The diagnosis was confirmed by occupational-type provocation tests in all workers with colophony-based cored solder, and reproduced by exposure to the fumes of heated colophony alone. Control subjects did not react to the test with colophony. The clinical findings and provocation test reactins have features of a hypersensitivity reaction, although so far specific antibodies have not been found.
本文描述了21名在电子行业工作并接触含有松香（松树树脂）的助焊剂烟雾后出现哮喘或外周气道反应迹象的患者。该特定群体中有5名患者既往有哮喘病史。14名患者从不吸烟。对常见环境抗原进行点刺试验，9名患者出现一种或多种阳性反应。对所有使用含松香芯焊料的工人进行职业性激发试验，确诊了该疾病，且仅接触加热松香烟雾也会再次引发该疾病。对照受试者对松香试验无反应。尽管目前尚未发现特异性抗体，但临床发现和激发试验反应具有超敏反应的特征。
