通过酶联免疫吸附测定法（ELISA）对淋病进行血清学诊断。
Serological diagnosis of gonorrhoea by an enzyme-linked immunosorbent assay (Elisa).
作者信息
Glynn A A, Ison C
出版信息
Br J Vener Dis. 1978 Apr;54(2):97-102. doi: 10.1136/sti.54.2.97.
Abstract
IgG antibody to an outer membrane protein extracted from Neisseria gonorrhoeae was measured in patients with gonorrhoea. The level in such patients was significantly higher than in normal controls or in patients with other conditions who were attending the clinic for sexually transmitted diseases. Significantly higher antibody levels were detectable in half the patients within a few days of infection and in a similar proportion of carriers--both male and female. Men with rectal gonorrhoea had particularly high antibody levels. Sixteen per cent of presumptively normal men and 11% of normal women gave positive results but the actual false positive rate could be lower.
摘要
对从淋病奈瑟菌中提取的一种外膜蛋白的IgG抗体在淋病患者中进行了检测。此类患者体内的抗体水平显著高于正常对照组或前来诊所就诊的其他性传播疾病患者。在感染后的几天内，半数患者以及相似比例的携带者（包括男性和女性）体内可检测到显著更高的抗体水平。患有直肠淋病的男性抗体水平尤其高。16%的推定正常男性和11%的正常女性检测结果呈阳性，但实际的假阳性率可能更低。
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