免疫球蛋白基因的组织：小鼠κ链恒定区基因的重复频率
Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene.
作者信息
Honjo T, Packman S, Swan D, Nau M, Leder P
出版信息
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3659-63. doi: 10.1073/pnas.71.9.3659.
Abstract
Hybridization kinetic analyses with synthetic DNA indicate that there are only two to three copies of the kappa constant region gene per haploid genome. This result lends weight to the argument that the immunoglobulin light chain is encoded by more than one continuous gene sequence.
摘要
用合成DNA进行的杂交动力学分析表明，单倍体基因组中κ恒定区基因只有两到三个拷贝。这一结果支持了免疫球蛋白轻链由多个连续基因序列编码的观点。
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