• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Delayed-type hypersensitivity against Semliki Forest virus in mice.小鼠对Semliki森林病毒的迟发型超敏反应。
Infect Immun. 1979 Feb;23(2):219-23. doi: 10.1128/iai.23.2.219-223.1979.
2
Cellular immunity against Semliki Forest virus in mice.小鼠对塞姆利基森林病毒的细胞免疫
Infect Immun. 1979 Feb;23(2):213-8. doi: 10.1128/iai.23.2.213-218.1979.
3
Dimethyl dioctadecyl ammoniumbromide as an adjuvant for delayed type hypersensitivity and cellular immunity against Semliki Forest virus in mice.二甲基二十八烷基溴化铵作为小鼠迟发型超敏反应和针对塞姆利基森林病毒细胞免疫的佐剂
Arch Virol. 1980;65(3-4):211-7. doi: 10.1007/BF01314537.
4
Delayed type hypersensitivity against semliki forest virus in mice: local transfer of delayed type hypersensitivity with thioglycollate-induced peritoneal exudate cells.小鼠对半里基森林病毒的迟发型超敏反应：用巯基乙酸诱导的腹腔渗出细胞进行迟发型超敏反应的局部转移。
Int Arch Allergy Appl Immunol. 1984;73(4):342-6. doi: 10.1159/000233495.
5
Delayed-type hypersensitivity in mice after infection with avirulent Semliki Forest virus. Brief report.
Arch Virol. 1983;78(1-2):115-8. doi: 10.1007/BF01310865.
6
A delayed-type hypersensitivity-inducing T-cell epitope of Semliki Forest virus mediates effective T-helper activity for antibody production.塞姆利基森林病毒的一种迟发型超敏反应诱导性T细胞表位介导抗体产生的有效辅助性T细胞活性。
Immunology. 1992 Nov;77(3):322-9.
7
Adjuvant effects of dimethyl dioctadecyl ammonium bromide, complete Freund's adjuvant and aluminium hydroxide on neutralizing antibody, antibody-isotype and delayed-type hypersensitivity responses to Semliki Forest virus in mice.二甲基二十八烷基溴化铵、完全弗氏佐剂和氢氧化铝对小鼠抗Semliki森林病毒中和抗体、抗体亚型及迟发型超敏反应的佐剂效应
FEMS Microbiol Immunol. 1991 Nov;3(6):305-20. doi: 10.1111/j.1574-6968.1991.tb04255.x.
8
Induction and characterization of delayed-type hypersensitivity to dengue virus in mice.小鼠对登革病毒迟发型超敏反应的诱导与表征
J Infect Dis. 1982 Aug;146(2):235-42. doi: 10.1093/infdis/146.2.235.
9
The effect of liposomal charge on the neutralizing antibody response against inactivated encephalomyocarditis and Semliki Forest viruses.脂质体电荷对针对灭活脑心肌炎病毒和塞姆利基森林病毒的中和抗体反应的影响。
Clin Exp Immunol. 1984 Jun;56(3):509-14.
10
Modulation of adjuvant-enhanced delayed-type hypersensitivity by the interferon inducers poly I:C and Newcastle disease virus.干扰素诱导剂聚肌胞苷酸和新城疫病毒对佐剂增强的迟发型超敏反应的调节作用
Int Arch Allergy Appl Immunol. 1986;79(1):86-9. doi: 10.1159/000233948.

引用本文的文献

1
Pathogenesis of virus-induced demyelination.病毒诱导的脱髓鞘病变的发病机制。
Adv Virus Res. 1993;42:249-324. doi: 10.1016/s0065-3527(08)60087-1.
2
Dimethyl dioctadecyl ammoniumbromide as an adjuvant for delayed type hypersensitivity and cellular immunity against Semliki Forest virus in mice.二甲基二十八烷基溴化铵作为小鼠迟发型超敏反应和针对塞姆利基森林病毒细胞免疫的佐剂
Arch Virol. 1980;65(3-4):211-7. doi: 10.1007/BF01314537.
3
Specificity, Ly phenotype, and H-2 compatibility requirements of effector cells in delayed-type hypersensitivity responses to murine influenza virus infection.对鼠流感病毒感染的迟发型超敏反应中效应细胞的特异性、淋巴细胞表型及H-2相容性要求
J Exp Med. 1980 Apr 1;151(4):815-26. doi: 10.1084/jem.151.4.815.
4
Detection of Semliki Forest virus in cell culture by use of an enzyme immunoassay with peroxidase-labeled monoclonal antibodies specific for glycoproteins E1 and E2.利用针对糖蛋白E1和E2的过氧化物酶标记单克隆抗体的酶免疫测定法在细胞培养物中检测塞姆利基森林病毒。
J Clin Microbiol. 1984 Sep;20(3):387-90. doi: 10.1128/jcm.20.3.387-390.1984.
5
Delayed-type hypersensitivity in mice after infection with avirulent Semliki Forest virus. Brief report.
Arch Virol. 1983;78(1-2):115-8. doi: 10.1007/BF01310865.
6
Identification of distinct antigenic determinants on Semliki Forest virus by using monoclonal antibodies with different antiviral activities.通过使用具有不同抗病毒活性的单克隆抗体鉴定塞姆利基森林病毒上不同的抗原决定簇。
J Virol. 1984 Nov;52(2):575-82. doi: 10.1128/JVI.52.2.575-582.1984.
7
The effect of liposomal charge on the neutralizing antibody response against inactivated encephalomyocarditis and Semliki Forest viruses.脂质体电荷对针对灭活脑心肌炎病毒和塞姆利基森林病毒的中和抗体反应的影响。
Clin Exp Immunol. 1984 Jun;56(3):509-14.
8
Determination of inhibitory concentrations of antiviral agents in cell culture by use of an enzyme immunoassay with virus-specific, peroxidase-labeled monoclonal antibodies.利用病毒特异性过氧化物酶标记单克隆抗体的酶免疫测定法测定细胞培养中抗病毒剂的抑制浓度。
Antimicrob Agents Chemother. 1985 May;27(5):802-5. doi: 10.1128/AAC.27.5.802.
9
Rapid determination of neutralizing antibodies to Semliki Forest virus in serum by enzyme immunoassay in cell culture with virus-specific monoclonal antibodies.利用病毒特异性单克隆抗体通过细胞培养中的酶免疫测定法快速测定血清中针对Semliki森林病毒的中和抗体。
J Clin Microbiol. 1986 Oct;24(4):665-8. doi: 10.1128/jcm.24.4.665-668.1986.
10
Adoptive transfer of immunity against virulent Semliki Forest virus with immune spleen cells from mice infected with avirulent Semliki Forest virus.用感染无毒力塞姆利基森林病毒的小鼠的免疫脾细胞进行针对强毒力塞姆利基森林病毒免疫的过继转移。
Arch Virol. 1986;91(1-2):83-92. doi: 10.1007/BF01316730.

本文引用的文献

1
The histophysiology of the antibody response. II. Antibody responses and splenic plasma cell reaction in sublethally x-irradiated rabbits.抗体反应的组织生理学。II. 亚致死剂量X射线照射兔的抗体反应及脾浆细胞反应
Lab Invest. 1963 Feb;12:156-70.
2
Occurrence of delayed hypersensitivity during the development of Arthus type hypersensitivity.阿瑟斯型超敏反应发生过程中迟发型超敏反应的出现。
J Exp Med. 1958 Jan 1;107(1):109-24. doi: 10.1084/jem.107.1.109.
3
Plaque formation and isolation of pure lines with poliomyelitis viruses.脊髓灰质炎病毒的噬斑形成及纯系分离
J Exp Med. 1954 Feb;99(2):167-82. doi: 10.1084/jem.99.2.167.
4
Replication of Semliki Forest virus: an electron microscopic study.Semliki森林病毒的复制：一项电子显微镜研究。
Virology. 1967 May;32(1):128-43. doi: 10.1016/0042-6822(67)90261-9.
5
An autoclavable powdered culture medium for mammalian cells.
Proc Soc Exp Biol Med. 1968 Jan;127(1):335-6. doi: 10.3181/00379727-127-32685.
6
The virulence of original and derived strains of Semliki forest virus for mice, guinea-pigs and rabbits.塞姆利基森林病毒原始株及衍生株对小鼠、豚鼠和兔子的毒力。
J Gen Virol. 1971 Aug;12(2):141-60. doi: 10.1099/0022-1317-12-2-141.
7
Studies on the amphipathic nature of the membrane proteins in Semliki Forest virus.关于辛德毕斯病毒中膜蛋白两亲性的研究。
J Mol Biol. 1974 Jan 5;85(4):569-87. doi: 10.1016/0022-2836(74)90316-7.
8
Isolation and characterization of the membrane proteins of Semliki Forest virus.Semliki森林病毒膜蛋白的分离与鉴定
Virology. 1974 Oct;61(2):493-504. doi: 10.1016/0042-6822(74)90285-2.
9
Investigations into yellow fever virus and other arboviruses in the northern regions of Kenya.对肯尼亚北部地区黄热病病毒及其他虫媒病毒的调查。
Bull World Health Organ. 1970;42(5):787-95.
10
Host defenses during primary Venezuelan equine encephalomyelitis virus infection in mice. I. Passive transfer of protection with immune serum and immune cells.
J Immunol. 1973 May;110(5):1345-53.

小鼠对Semliki森林病毒的迟发型超敏反应。

Delayed-type hypersensitivity against Semliki Forest virus in mice.

作者信息

Kraaijeveld C A, Harmsen M, Khader Boutahar-Trouw B

出版信息

Infect Immun. 1979 Feb;23(2):219-23. doi: 10.1128/iai.23.2.219-223.1979.

DOI:10.1128/iai.23.2.219-223.1979
PMID:422238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC414151/
Abstract

After intracutaneous immunization with purified inactivated Semliki Forest virus, a delayed-type hypersensitivity without detectable antibodies in serum was obtained in BALB/c mice. Low doses of antigen given intraperitoneally induced antibodies. Intracutaneous immunization with much higher doses induced no specific antibodies, but a footpad swelling was observed after challenge with homolgous antigen. Pretreatment with cyclophosphamide before immunization enhanced footpad swelling. Microscopic examination of footpads from sensitized mice at 24 h after challenge showed a mononuclear infiltrate. The delayed-type reaction could be transferred to syngenic mice with lymph node cells, but not with spleen cells or serum. The biphasic character of the delayed-type hypersensitivity is discussed.

摘要

用纯化的灭活塞姆利基森林病毒进行皮内免疫后，BALB/c小鼠出现了血清中无可检测抗体的迟发型超敏反应。腹腔内注射低剂量抗原则诱导产生抗体。用高得多的剂量进行皮内免疫未诱导产生特异性抗体，但用同源抗原攻击后观察到足垫肿胀。免疫前用环磷酰胺预处理可增强足垫肿胀。攻击后24小时对致敏小鼠的足垫进行显微镜检查显示有单核细胞浸润。迟发型反应可通过淋巴结细胞转移给同基因小鼠，但不能通过脾细胞或血清转移。文中讨论了迟发型超敏反应的双相特征。