小鼠品系间巨噬细胞功能差异及其与抗体反应的关系。
Inter-mouse strain differences in macrophage function and its relationship to antibody responses.
作者信息
Passwell J H, Steward M W, Soothill J F
出版信息
Clin Exp Immunol. 1974 May;17(1):159-67.
Abstract
Macrohage function, as measured by carbon clearance, differs in different inbred strains. Low affinity () antibody response to HST is associated either with poor carbon clearance, or slow recovery from carbon blockade by macrophages. Carbon blockade reduces , but not Ab in mice with high carbon clearance and . Stilboestrol increases carbon clearance and in mice with slow clearance and low . The significance of these findings in pathogenesis and treatment of chronic soluble complex disease is discussed.
摘要
通过碳清除率测定的巨噬细胞功能在不同近交系中存在差异。对热稳定毒素（HST）的低亲和力抗体反应要么与碳清除率低有关，要么与巨噬细胞对碳阻断的恢复缓慢有关。碳阻断在碳清除率高的小鼠中会降低[具体指标未明确]，但不会降低抗体。己烯雌酚可提高碳清除率低且[具体指标未明确]低的小鼠的碳清除率和[具体指标未明确]。本文讨论了这些发现对慢性可溶性复合物疾病发病机制和治疗的意义。
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2
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Bacteriol Rev. 1964 Mar;28(1):30-71. doi: 10.1128/br.28.1.30-71.1964.
3
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Br Med J. 1963 Jul 6;2(5348):27-31. doi: 10.1136/bmj.2.5348.27.
4
Experimental glomerulonephritis. The pathogenesis of a laboratory model resembling the spectrum of human glomerulonephritis.实验性肾小球肾炎。一种类似于人类肾小球肾炎谱系的实验室模型的发病机制。
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