一种包膜支原体病毒超螺旋DNA基因组的物理特性分析
Physical characterization of the superhelical DNA genome of an enveloped mycoplasmavirus.
作者信息
Nowak J A, Maniloff J
出版信息
J Virol. 1979 Jan;29(1):374-80. doi: 10.1128/JVI.29.1.374-380.1979.
Abstract
Mycoplasmavirus MVL2 is a nonlytic enveloped virion containing DNA. This DNA has been shown to be a double-stranded circular superhelical molecule of 11.8 kilobase pairs (7.8 X 10(6) daltons). The superhelix density is greater than that of phi X174 RFI but less than that of PM2 phage DNA. A physical map of the MVL2 genome has been obtained using restriction endonucleases.
摘要
支原体病毒MVL2是一种含有DNA的非裂解性包膜病毒粒子。该DNA已被证明是一个11.8千碱基对（7.8×10⁶道尔顿）的双链环状超螺旋分子。其超螺旋密度大于φX174 RFI，但小于PM2噬菌体DNA。已使用限制性内切酶获得了MVL2基因组的物理图谱。
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