单链RNA病毒基因组中信使RNA功能与富含腺苷酸片段的相关性。
Correlation of messenger RNA function with adenylate-rich segments in the genomes of single-stranded RNA viruses.
作者信息
Johnston R E, Bose H R
出版信息
Proc Natl Acad Sci U S A. 1972 Jun;69(6):1514-6. doi: 10.1073/pnas.69.6.1514.
Abstract
Oligonucleotides enriched in adenylate residues have been demonstrated in the genomes of two positive-strand RNA viruses, Sindbis and Columbia SK. Such oligonucleotides were not found in the genome of vesicular stomatitis virus, a negative-strand virus. The adenylate-rich oligonucleotides from Sindbis and Columbia SK viruses appeared similar when analyzed by zonal sedimentation in sucrose-sodium dodecyl sulfate.
摘要
富含腺苷酸残基的寡核苷酸已在两种正链RNA病毒——辛德毕斯病毒和哥伦比亚SK病毒的基因组中得到证实。而在负链病毒水疱性口炎病毒的基因组中未发现此类寡核苷酸。当通过蔗糖-十二烷基硫酸钠区带沉降分析时，来自辛德毕斯病毒和哥伦比亚SK病毒的富含腺苷酸的寡核苷酸看起来相似。
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