猴病毒40脱氧核糖核酸转录模式。II. 在转化细胞中。
Patterns of simian virus 40 deoxyribonucleic acid transcription. II. In transformed cells.
作者信息
Khoury G, Byrne J C, Takemoto K K, Martin M A
出版信息
J Virol. 1973 Jan;11(1):54-60. doi: 10.1128/JVI.11.1.54-60.1973.
Abstract
The pattern of simian virus 40 (SV40) deoxyribonucleic acid transcription has been examined in 11 SV40-transformed cell lines. In all cases, substantial regions of the minus strand (35-75%) appeared to be transcribed. In the lines tested, these regions included the "early" gene sequences. The SV40-specific ribonucleic acid from at least two of the transformed cell lines represented significantly greater portions of the minus strand than are represented in "early" lytic ribonucleic acid. Small regions of the plus strand appeared to be transcribed in only two of the transformed cell lines.
摘要
已对11种猿猴病毒40（SV40）转化的细胞系中SV40脱氧核糖核酸转录模式进行了检测。在所有情况下，负链的大部分区域（35%-75%）似乎都被转录。在所检测的细胞系中，这些区域包括“早期”基因序列。来自至少两种转化细胞系的SV40特异性核糖核酸在负链中所占比例明显高于“早期”裂解核糖核酸中的比例。正链的小区域似乎仅在两种转化细胞系中被转录。
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