牛Thiry空肠瘘对产气荚膜梭菌肠毒素的液体分泌反应。
Fluid secretory response of bovine Thiry jejunal fistula to enterotoxin of Clostridium perfringens.
作者信息
Niilo L
出版信息
Infect Immun. 1973 Jan;7(1):1-4. doi: 10.1128/iai.7.1.1-4.1973.
Abstract
The effect of enterotoxin of Clostridium perfringens type A was studied in Thiry fistula of the bovine jejunum. Accumulation of fluid as a pathological response was demonstrable within 30 min after introduction of enterotoxin into the fistula; the fluid volume increased rapidly within the first 2 hr and reached maximum in 7 hr. The enterotoxin was not destroyed by the jejunal fluid; 52% of it was absorbed in 2 to 3 hr, and all of the enterotoxin was taken up within 8 hr postinoculation. The accumulation of fluid by the fistula after 0.5 to 2 hr of exposure to enterotoxin ceased completely within 5 hr.
摘要
在牛空肠的Thiry瘘管中研究了A型产气荚膜梭菌肠毒素的作用。将肠毒素引入瘘管后30分钟内即可证明有作为病理反应的液体蓄积；在前2小时内液体量迅速增加，并在7小时达到最大值。空肠液不会破坏肠毒素；其中52%在2至3小时内被吸收，接种后8小时内所有肠毒素均被吸收。暴露于肠毒素0.5至2小时后瘘管内的液体蓄积在5小时内完全停止。
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