BK病毒（一种人乳头多瘤病毒）导致BHK21克隆13细胞的恶性转化
Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus.
作者信息
Major E O, Di Mayorca G
出版信息
Proc Natl Acad Sci U S A. 1973 Nov;70(11):3210-2. doi: 10.1073/pnas.70.11.3210.
Abstract
BK virus, a widespread human papovavirus, is shown to cause malignant transformation of BHK(21) clone 13 cells. The transformed cells grow as tumors upon inoculation in adult hamsters. The question of the possible role of this virus in human neoplasia is raised.
摘要
BK病毒是一种广泛传播的人乳头多瘤空泡病毒，已证实它可导致幼仓鼠肾（BHK）（21）克隆13细胞发生恶性转化。接种到成年仓鼠体内后，这些转化细胞会形成肿瘤。由此引发了关于该病毒在人类肿瘤形成中可能作用的问题。
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