人巨细胞病毒。II. 与单纯疱疹病毒I型和II型、爱泼斯坦-巴尔病毒及非人巨细胞病毒株的DNA无相关性。
Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II, Epstein-Barr virus, and nonhuman strains of cytomegalovirus.
作者信息
Huang E S, Pagano J S
出版信息
J Virol. 1974 Mar;13(3):642-5. doi: 10.1128/JVI.13.3.642-645.1974.
Abstract
The purified DNA of human cytomegalovirus, radiolabeled in vitro, was examined for homology to Epstein-Barr virus, herpes simplex type I and II, and simian and murine cytomegalovirus DNA by DNA-DNA reassociation kinetics analyses with the S1 enzyme differential digestion technique. Cross-matching of the DNAs showed no relatedness or less than 5% detectable homology.
摘要
采用S1酶差异消化技术，通过DNA-DNA重缔合动力学分析，对体外放射性标记的人巨细胞病毒纯化DNA与爱泼斯坦-巴尔病毒、单纯疱疹病毒I型和II型以及猿猴和鼠类巨细胞病毒DNA的同源性进行了检测。DNA的交叉匹配显示无相关性或可检测到的同源性低于5%。
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