Horwitz M S
J Virol. 1974 May;13(5):1046-54. doi: 10.1128/JVI.13.5.1046-1054.1974.
Utilizing the isolated left and right halves of both adenovirus type 2 and the nondefective adenovirus simian virus 40 hybrid (Ad2(+)ND(1)), studies were undertaken to find the site on the DNA molecules at which replication begins. The data are consistent with several models which include an initiation event at both ends and bidirectional growth.
利用2型腺病毒和无缺陷腺病毒猿猴病毒40杂交体(Ad2(+)ND(1))分离出的左右两半部分,开展了研究以寻找DNA分子上复制起始的位点。数据与几个模型相符,这些模型包括两端的起始事件和双向生长。