用单剂量短效磺胺类药物治疗的尿路感染
Urinary tract infections treated with single dose of short-acting sulphonamide.
作者信息
Källenius G, Winberg J
出版信息
Br Med J. 1979 May 5;1(6172):1175-6. doi: 10.1136/bmj.1.6172.1175.
Abstract
In a prospective study 29 patients with urinary tract infections caused by sulphonamide-sensitive organisms were treated with a single oral dose of the short-acting sulphonamide sulphafurazole. Twenty-seven (93%) of the 29 patients--and possibly all 29--were cured of their infections. There was no difference in the recurrence rates after single-dose treatment and treatment for 10 days or more. Six out of eight strains of Escherichia coli causing early recurrences were sensitive to sulphonamides. These results suggest that uncomplicated infections may safely and successfully be treated by a single oral dose of a short-acting sulphonamide.
摘要
在一项前瞻性研究中，29例由对磺胺类药物敏感的微生物引起的尿路感染患者接受了单剂量口服短效磺胺类药物磺胺异恶唑的治疗。29例患者中有27例（93%）——可能全部29例——感染得到治愈。单剂量治疗与治疗10天或更长时间后的复发率没有差异。导致早期复发的8株大肠杆菌中有6株对磺胺类药物敏感。这些结果表明，单纯性感染可以通过单剂量口服短效磺胺类药物安全、成功地进行治疗。
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本文引用的文献
1
2
Single-dose treatment of acute urinary tract infection: a controlled trial.急性尿路感染的单剂量治疗：一项对照试验。
Br Med J. 1967 Sep 9;3(5566):649-51. doi: 10.1136/bmj.3.5566.649.
3
Studies of urinary tract infections in infancy and childhood. 8. Reinfection vs. relapse in recurrent urinary tract infections. Evaluation by means of identification of infecting organisms.婴幼儿尿路感染的研究。8. 复发性尿路感染中的再感染与复发。通过鉴定感染病原体进行评估。
J Pediatr. 1967 Jul;71(1):13-20. doi: 10.1016/s0022-3476(67)80224-5.
4
Resistant urinary infections resulting from changes in resistance pattern of faecal flora induced by sulphonamide and hospital environment.由磺胺类药物和医院环境引起的粪便菌群耐药模式改变导致的耐药性泌尿系统感染。
Br Med J. 1970 Aug 8;3(5718):305-9. doi: 10.1136/bmj.3.5718.305.
5
Studies of urinary tract infections in infancy and childhood. X. Short or long-term treatment in girls with first or second-time urinary tract infections uncomplicated by obstructive urological abnormalities.
Acta Paediatr Scand. 1968 May;57(3):186-94. doi: 10.1111/j.1651-2227.1968.tb04677.x.
6
Antibiotic sensitivity testing. Report of an international collaborative study.抗生素敏感性试验。一项国际合作研究报告。
Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217:Suppl 217:1+.
7
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JAMA. 1976 Apr 26;235(17):1854-6.
8
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9
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