Burgoyne L A, Hewish D R, Mobbs J
Biochem J. 1974 Oct;143(1):67-72. doi: 10.1042/bj1430067.
The basic regularity of chromatin substructure that has been reported in rat liver chromatin (Hewish & Burgoyne, 1973b) was also detected in mouse chromatin. The regular series of DNA fragments produced by the action of Ca-Mg endonuclease on rat chromatin were studied further. The smallest single-stranded class has a molecular weight of approx. 45000-63000 and the smallest double-stranded class has a molecular weight of approx. 120000-150000. Studies of the substructure of the DNA fragments produced by the Ca-Mg endonuclease have shown that the regular series of double-stranded fragments have regular series of single-stranded fragments within them. It was concluded that the regular series of double-stranded fragments was probably a consequence of the regular series of single-stranded fragments. Digestion time-courses are presented for mouse and rat nuclear DNA.
在大鼠肝脏染色质中报道的染色质亚结构的基本规律（休伊什和伯戈因，1973b）在小鼠染色质中也被检测到。对钙 - 镁内切核酸酶作用于大鼠染色质产生的一系列规则的DNA片段进行了进一步研究。最小的单链类别分子量约为45000 - 63000，最小的双链类别分子量约为120000 - 150000。对钙 - 镁内切核酸酶产生的DNA片段亚结构的研究表明，规则的双链片段系列中包含规则的单链片段系列。得出的结论是，规则的双链片段系列可能是规则的单链片段系列的结果。给出了小鼠和大鼠核DNA的消化时间进程。
