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Modification of delta9-THC-actions by cannabinol and cannabidiol in the rat.

作者信息

Fernandes M, Schabarek A, Coper H, Hill R

出版信息

Psychopharmacologia. 1974;38(4):329-38. doi: 10.1007/BF00429130.

DOI:10.1007/BF00429130
PMID:4473791
Abstract
摘要

相似文献

1
Modification of delta9-THC-actions by cannabinol and cannabidiol in the rat.大麻酚和大麻二酚对大鼠体内δ9-四氢大麻酚作用的修饰。
Psychopharmacologia. 1974;38(4):329-38. doi: 10.1007/BF00429130.
2
Interaction of delta9-tetrahydrocannabinol and cannabidiol on intestinal motility in mice.
J Pharm Pharmacol. 1974 Feb;26(2):136-7. doi: 10.1111/j.2042-7158.1974.tb09240.x.
3
A study of the development of tolerance to an anticonvulsant effect of delta9-tetrahydrocannabinol and cannabidiol.一项关于对δ9-四氢大麻酚和大麻二酚抗惊厥作用耐受性发展的研究。
Res Commun Chem Pathol Pharmacol. 1974 Sep;9(1):23-39.
4
Effect of subchronic treatment with (-) 8 -trans-tetrahydrocannabinol ( 8 -THC) on food intake, body temperature, hexobarbital sleeping time and hexobarbital elimination in rats.(-)8-反式-四氢大麻酚（8-THC）亚慢性治疗对大鼠食物摄入量、体温、己巴比妥睡眠时间和己巴比妥消除的影响。
Psychopharmacologia. 1972;27(4):349-57. doi: 10.1007/BF00429388.
5
Cannabidiol interaction with delta9-tetrahydrocannabinol.
Res Commun Chem Pathol Pharmacol. 1974 Apr;7(4):663-70.
6
Interactions in man of delta-9-tetrahydrocannabinol. II. Cannabinol and cannabidiol.人源中δ-9-四氢大麻酚的相互作用。II. 大麻酚和大麻二酚。
Clin Pharmacol Ther. 1975 Jul;18(1):80-3. doi: 10.1002/cpt197518180.
7
Marihuana-like activity of new synthetic tetrahydrocannabinols.
Pharmacol Biochem Behav. 1975 Sep-Oct;3(5):849-53. doi: 10.1016/0091-3057(75)90116-1.
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Pharmacologic interaction between cannabinol and delta9-tetrahydrocannabinol.大麻酚与δ9-四氢大麻酚之间的药理相互作用。
Psychopharmacologia. 1975;41(3):277-84. doi: 10.1007/BF00428937.
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Absence of interaction between delta9-tetrahydrocannabinol (delta-THC) and cannabidiol (CBD) in aggression, muscle control and body temperature experiments in mice.在小鼠的攻击行为、肌肉控制和体温实验中，δ9-四氢大麻酚（δ-THC）与大麻二酚（CBD）之间不存在相互作用。
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Effect of acute and chronic pretreatment with delta1-tetrahydrocannabinol on motor impairment by ethanol in the rat.
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Transfer of cannabinoids into the milk of dairy cows fed with industrial hemp could lead to Δ-THC exposure that exceeds acute reference dose.给奶牛喂食工业大麻会导致大麻素转移到牛奶中，从而使奶牛体内的 Δ-THC 暴露量超过急性参考剂量。
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THC and CBD: Villain versus Hero? Insights into Adolescent Exposure.THC 和 CBD：反派与英雄？青少年接触的深入洞察。
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Cannabidiol and Delta-9-Tetrahydrocannabinol Interactions in Male and Female Rats With Persistent Inflammatory Pain.

本文引用的文献

1
[Active principals of the cannabis and the pharmacology of the cannabinols].[大麻的活性成分及大麻酚类的药理学]
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1950;211(2):175-93.
2
Activity of delta8- and delta9-tetrahydrocannabinol and related compounds in the mouse.δ8-和δ9-四氢大麻酚及相关化合物在小鼠体内的活性。
Science. 1971 Apr 9;172(3979):165-7. doi: 10.1126/science.172.3979.165.
3
Structure activity relationship of four tetrahydrocannabinols and the pharmacological activity of five semi-purified extracts of Cannabis sativa.
大麻二酚与Δ9-四氢大麻酚在慢性炎性痛雄性和雌性大鼠体内的相互作用
J Pain. 2023 Jan;24(1):98-111. doi: 10.1016/j.jpain.2022.09.002. Epub 2022 Sep 16.
4
TRPV1: A Common Denominator Mediating Antinociceptive and Antiemetic Effects of Cannabinoids.TRPV1：大麻素介导的抗伤害感受和止吐作用的共同介质。
Int J Mol Sci. 2022 Sep 2;23(17):10016. doi: 10.3390/ijms231710016.
5
Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses.次要大麻素：生物合成、分子药理学及潜在治疗用途
Front Pharmacol. 2021 Nov 29;12:777804. doi: 10.3389/fphar.2021.777804. eCollection 2021.
6
Safety and tolerability of escalating cannabinoid doses in healthy cats.在健康猫中递增大麻素剂量的安全性和耐受性。
J Feline Med Surg. 2021 Dec;23(12):1162-1175. doi: 10.1177/1098612X211004215. Epub 2021 Mar 26.
7
Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals.大麻素激动剂和拮抗剂对实验动物睡眠的影响。
Adv Exp Med Biol. 2021;1297:97-109. doi: 10.1007/978-3-030-61663-2_7.
8
Preliminary Investigation of the Safety of Escalating Cannabinoid Doses in Healthy Dogs.健康犬类中大麻素剂量递增安全性的初步研究。
Front Vet Sci. 2020 Feb 11;7:51. doi: 10.3389/fvets.2020.00051. eCollection 2020.
9
Effectiveness and tolerability of THC:CBD oromucosal spray as add-on measure in patients with severe chronic pain: analysis of 12-week open-label real-world data provided by the German Pain e-Registry.四氢大麻酚：大麻二酚口腔黏膜喷雾剂作为重度慢性疼痛患者附加治疗措施的有效性和耐受性：对德国疼痛电子注册库提供的12周开放标签真实世界数据的分析
J Pain Res. 2019 May 20;12:1577-1604. doi: 10.2147/JPR.S192174. eCollection 2019.
10
Delta-9-tetrahydrocannabinol and cannabidiol: Separating the chemicals from the "weed," a pharmacodynamic discussion.Δ-9-四氢大麻酚和大麻二酚：从“杂草”中分离化学物质，药效学探讨
Ment Health Clin. 2016 Nov 3;6(6):277-284. doi: 10.9740/mhc.2016.11.277. eCollection 2016 Nov.
四种四氢大麻酚的构效关系及五种大麻半纯化提取物的药理活性
Psychopharmacologia. 1970 Aug 19;18(1):82-93. doi: 10.1007/BF00402387.
4
Acute tolerance to the hypothermic effect of marihuana in the rat.大鼠对大麻低温效应的急性耐受性。
Res Commun Chem Pathol Pharmacol. 1971 Mar;2(2):159-67.
5
Blockade of (-)-trans- 9 -tetrahydrocannabinol depressant effect by cannabinol in mice.
Am J Pharm Sci Support Public Health. 1971 Sep-Oct;143(5):149-52.
6
A metabolic interaction in vivo between cannabidiol and 1 -tetrahydrocannabinol.大麻二酚与1-四氢大麻酚在体内的代谢相互作用。
Br J Pharmacol. 1972 Jun;45(2):375-7. doi: 10.1111/j.1476-5381.1972.tb08092.x.
7
Comparison of behavioral effects of synthetic (-) 9 -trans-tetrahydrocannabinol and marihuana extract distillate in chimpanzees.合成（-）9-反式四氢大麻酚与大麻提取物馏出物对黑猩猩行为影响的比较。
Psychopharmacologia. 1972;25(2):169-74. doi: 10.1007/BF00423194.
8
Marihuana in man: three years later.人类使用大麻：三年之后。
Science. 1971 Apr 2;172(3978):21-9. doi: 10.1126/science.172.3978.21.
9
Marihuana chemistry.大麻化学
Science. 1970 Jun 5;168(3936):1159-66. doi: 10.1126/science.168.3936.1159.
10
Interactions of several cannabinoids with the hepatic drug metabolizing system.几种大麻素与肝脏药物代谢系统的相互作用。
Biochem Pharmacol. 1973 Dec 1;22(23):2981-7. doi: 10.1016/0006-2952(73)90184-6.