病毒感染期间的免疫球蛋白E反应。
Immunoglobulin E response during viral infections.
作者信息
Perelmutter L, Potvin L, Phipps P
出版信息
J Allergy Clin Immunol. 1979 Aug;64(2):127-30. doi: 10.1016/0091-6749(79)90046-0.
Abstract
One hundred and three patients (90 nonatopics and 13 atopics) with respiratory infections to various viral agents were studied retrospectively with respect to IgE immunoglobulin levels during acute (1 to 7 days) and convalescent (8 to 30 days) phases of infection. It was found that 59% of patients had a decrease of 20% or more in IgE level, 27% remained the same, and only 14% showed a rise 20% or more from the acute to the convalescent phases of infection. IgE levels decreased up to 3 to 4 wk after symptoms and the degree of decrease was more apparent for the nonatopics who had higher IgE levels in their acute phase of infection. Less dramatic decrease in IgE was observed for the 13 atopics studied. The changes in IgE levels during the viral infectious period are discussed in terms of possible cellular mechanisms that may control IgE immunoglobulin.
摘要
对103例（90例非特应性患者和13例特应性患者）感染各种病毒病原体的呼吸道感染患者，回顾性研究了其在感染急性期（1至7天）和恢复期（8至30天）的IgE免疫球蛋白水平。结果发现，59%的患者IgE水平下降了20%或更多，27%保持不变，只有14%的患者从感染急性期到恢复期IgE水平上升了20%或更多。症状出现后3至4周内IgE水平下降，非特应性患者在感染急性期IgE水平较高，其下降程度更为明显。在研究的13例特应性患者中，观察到IgE下降不太显著。从可能控制IgE免疫球蛋白的细胞机制方面讨论了病毒感染期IgE水平的变化。
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