Suppr超能文献

噬菌体φX174中的基因重组

Genetic recombination in bacteriophage phi chi 174.

作者信息

Benbow R M, Zuccarelli A J, Davis G C, Sinsheimer R L

出版信息

J Virol. 1974 Apr;13(4):898-907. doi: 10.1128/JVI.13.4.898-907.1974.

Abstract

Genetic recombination in bacteriophage phiX174 usually takes place early in the infection process and involves two parental replicative form (double-stranded) DNA molecules. The host recA protein is required; none of the nine known phiX174 cistron products is essential. The products of a single recombination event are nonreciprocal and asymmetric. Typically, only one of the parental genotypes and one recombinant genotype are recovered from a single cell. An alternative, less efficient recombination mechanism which requires an active phiX174 cistron A protein is observed in the absence of the host recA gene product.

摘要

噬菌体φX174中的基因重组通常发生在感染过程的早期,涉及两个亲本复制型(双链)DNA分子。宿主recA蛋白是必需的;已知的9个φX174顺反子产物中没有一个是必不可少的。单次重组事件的产物是非互惠且不对称的。通常,从单个细胞中只能回收一种亲本基因型和一种重组基因型。在没有宿主recA基因产物的情况下,会观察到另一种效率较低的重组机制,该机制需要有活性的φX174顺反子A蛋白。

相似文献

1
Genetic recombination in bacteriophage phi chi 174.噬菌体φX174中的基因重组
J Virol. 1974 Apr;13(4):898-907. doi: 10.1128/JVI.13.4.898-907.1974.
2
Recombinant DNA molecules of bacteriophage phi chi174.噬菌体φX174的重组DNA分子。
Proc Natl Acad Sci U S A. 1975 Jan;72(1):235-9. doi: 10.1073/pnas.72.1.235.

引用本文的文献

7
A cleavage map of bacteriophage phiX174 genome.噬菌体φX174基因组的切割图谱。
Proc Natl Acad Sci U S A. 1974 Jul;71(7):2882-6. doi: 10.1073/pnas.71.7.2882.

本文引用的文献

2
Genetic Map of Bacteriophage phiX174.噬菌体φX174的遗传图谱
J Virol. 1971 May;7(5):549-58. doi: 10.1128/JVI.7.5.549-558.1971.
5
COMPLEMENTATION GROUPS IN PHAGE S13.噬菌体S13中的互补群
Virology. 1965 Feb;25:303-21. doi: 10.1016/0042-6822(65)90208-4.
9
Genetic recombination in phage S13.噬菌体S13中的基因重组
Virology. 1959 Apr;7(4):465-7. doi: 10.1016/0042-6822(59)90075-3.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验