维生素A对免疫反应的影响。
Influence of vitamin A on immunological response.
作者信息
Jurin M, Tannock I F
出版信息
Immunology. 1972 Sep;23(3):283-7.
Abstract
The influence of vitamin A injections on immunological response in mice was investigated. Two end-points were used: the titre of haemagglutinin at 10 or 15 days after sensitization with sheep red blood cells (SRBC), and the time to reject C57BL/6 male skin grafts by isologous female recipients. Daily vitamin A injections for the 5 days preceding or following sensitization with SRBC led to a large increase in the production of haemagglutinin antibodies. Injection of vitamin A for the 5 days preceding or following grafting, or starting on the 6th day after grafting, significantly reduced the mean rejection time of male skin grafts.
摘要
研究了维生素A注射对小鼠免疫反应的影响。采用了两个终点指标：用绵羊红细胞（SRBC）致敏后10天或15天的血凝素滴度，以及同基因雌性受体排斥C57BL/6雄性皮肤移植物的时间。在SRBC致敏前或致敏后的5天内每日注射维生素A，导致血凝素抗体产生大幅增加。在移植前或移植后的5天内注射维生素A，或在移植后第6天开始注射，显著缩短了雄性皮肤移植物的平均排斥时间。
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