RNA肿瘤病毒的RNA依赖性DNA聚合酶活性。V. 感染鸡胚成纤维细胞中的劳斯肉瘤病毒单链RNA-DNA共价杂交体。
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells.
作者信息
Leis J, Schincariol A, Ishizaki R, Hurwitz J
出版信息
J Virol. 1975 Mar;15(3):484-9. doi: 10.1128/JVI.15.3.484-489.1975.
Abstract
RNA-DNA covalent hybrids containing viral RNA have been isolated from nuclear fractions of Rous sarcoma virus-infected chicken embryo fibroblast cells shortly after virus infection. The formation of covalent hybrid structures depends upon a functional reverse transcriptase in vivo, since its appearance in cells is temperature dependent when infected with Rous sarcoma virus mutant LA335, which contains a temperature-sensitive reverse transcriptase.
摘要
在感染劳斯肉瘤病毒后不久，已从感染该病毒的鸡胚成纤维细胞的核组分中分离出含有病毒RNA的RNA-DNA共价杂交体。共价杂交结构的形成取决于体内功能性逆转录酶，因为当用含有温度敏感型逆转录酶的劳斯肉瘤病毒突变体LA335感染细胞时，其在细胞中的出现与温度有关。
相似文献
1
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells.RNA肿瘤病毒的RNA依赖性DNA聚合酶活性。V. 感染鸡胚成纤维细胞中的劳斯肉瘤病毒单链RNA-DNA共价杂交体。
J Virol. 1975 Mar;15(3):484-9. doi: 10.1128/JVI.15.3.484-489.1975.
2
Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus.罗氏肉瘤病毒感染的鸡细胞中新合成的病毒特异性核糖核酸的定量测定与定位
J Virol. 1973 May;11(5):761-74. doi: 10.1128/JVI.11.5.761-774.1973.
3
Requirement for cell division for initiation of transcription of Rous sarcoma virus RNA.劳氏肉瘤病毒RNA转录起始对细胞分裂的需求。
J Virol. 1974 Sep;14(3):531-46. doi: 10.1128/JVI.14.3.531-546.1974.
4
Cell cycle-dependent activation of rous sarcoma virus-infected stationary chicken cells: avian leukosis virus group-specific antigens and ribonucleic acid.劳氏肉瘤病毒感染的静止鸡细胞的细胞周期依赖性激活：禽白血病病毒群特异性抗原和核糖核酸。
J Virol. 1972 Jul;10(1):82-7. doi: 10.1128/JVI.10.1.82-87.1972.
5
Ribonuclease-sensitive deoxyribonucleic acid polymerase activity in uninfected rat cells and rat cells infected with Rous sarcoma virus.未感染的大鼠细胞和感染劳氏肉瘤病毒的大鼠细胞中对核糖核酸酶敏感的脱氧核糖核酸聚合酶活性
J Virol. 1971 Nov;8(5):630-42. doi: 10.1128/JVI.8.5.630-642.1971.
6
Assay of noninfectious fragments of DNA of avian leukosis virus-infected cells by marker rescue.通过标记拯救法检测禽白血病病毒感染细胞的非感染性DNA片段
J Virol. 1977 May;22(2):300-7. doi: 10.1128/JVI.22.2.300-307.1977.
7
Mechanism of transfection of chicken embryo fibroblasts by Rous sarcoma virus DNA.劳氏肉瘤病毒DNA转染鸡胚成纤维细胞的机制。
J Virol. 1978 Oct;28(1):45-52. doi: 10.1128/JVI.28.1.45-52.1978.
8
A replication defective mutant of Rous sarcoma virus which fails to make a functional reverse transcriptase.劳氏肉瘤病毒的一种复制缺陷型突变体，该突变体无法产生有功能的逆转录酶。
Virology. 1975 Mar;64(1):49-62. doi: 10.1016/0042-6822(75)90078-1.
9
Virus-specific ribonucleic acid in cells producing rous sarcoma virus: detection and characterization.产生劳氏肉瘤病毒的细胞中的病毒特异性核糖核酸：检测与特性分析
J Virol. 1972 Jun;9(6):891-902. doi: 10.1128/JVI.9.6.891-902.1972.
10
Hybridization of Rous sarcoma virus deoxyribonucleic acid polymerase product and ribonucleic acids from chicken and rat cells infected with Rous sarcoma virus.劳氏肉瘤病毒脱氧核糖核酸聚合酶产物与感染劳氏肉瘤病毒的鸡和大鼠细胞的核糖核酸的杂交
J Virol. 1972 May;9(5):766-75. doi: 10.1128/JVI.9.5.766-775.1972.
引用本文的文献
1
Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus.在感染禽肉瘤病毒和小鼠乳腺肿瘤病毒的细胞中逆转录病毒DNA正链的合成。
J Virol. 1981 Jan;37(1):127-38. doi: 10.1128/JVI.37.1.127-138.1981.
2
tRNA's associated with the 70S RNA of avian myeloblastosis virus.与禽成髓细胞瘤病毒70S RNA相关的转运RNA
J Virol. 1975 Dec;16(6):1608-14. doi: 10.1128/JVI.16.6.1608-1614.1975.
3
Kinetics of murine type C virus-specific DNA synthesis newly infected cells.新感染细胞中鼠C型病毒特异性DNA合成的动力学
J Virol. 1975 Oct;16(4):824-31. doi: 10.1128/JVI.16.4.824-831.1975.
4
Fate of input oncornavirion RNA--biological studies.输入的肿瘤病毒RNA的命运——生物学研究
J Virol. 1976 Apr;18(1):85-91. doi: 10.1128/JVI.18.1.85-91.1976.
5
Inhibition of oncornavirus functions by poly (2-methylthioinosinic acid).聚（2-甲硫基肌苷酸）对肿瘤病毒功能的抑制作用
Nucleic Acids Res. 1975 Dec;2(12):2305-13. doi: 10.1093/nar/2.12.2305.
6
Thermolabile reverse transcriptase of a mammalian leukemia virus mutant temperature sensitive in its replication and sarcoma virus helper functions.一种在复制和肉瘤病毒辅助功能方面对温度敏感的哺乳动物白血病病毒突变体的热不稳定逆转录酶。
J Virol. 1975 Dec;16(6):1476-82. doi: 10.1128/JVI.16.6.1476-1482.1975.
本文引用的文献
1
EFFECTS OF ACTINOMYCIN D AND OF MITOMYCIN C ON THE DEVELOPMENT OF ROUS SARCOMA VIRUS.放线菌素D和丝裂霉素C对劳斯肉瘤病毒发育的影响
Virology. 1964 Aug;23:511-9. doi: 10.1016/0042-6822(64)90235-1.
2
THE PARTICIPATION OF DNA IN ROUS SARCOMA VIRUS PRODUCTION.DNA在劳氏肉瘤病毒产生过程中的作用。
Virology. 1964 Aug;23:486-94. doi: 10.1016/0042-6822(64)90232-6.
3
THE ROLE OF DEOXYRIBONUCLEIC ACID IN THE SYNTHESIS OF ROUS SARCOMA VIRUS.脱氧核糖核酸在劳斯肉瘤病毒合成中的作用
Virology. 1964 Apr;22:462-8. doi: 10.1016/0042-6822(64)90067-4.
4
RNA metabolism in the HeLa cell nucleus.海拉细胞核中的RNA代谢
J Mol Biol. 1966 May;17(1):117-30. doi: 10.1016/s0022-2836(66)80098-0.
5
Host restriction of friend leukemia virus; fate of input virion RNA.宿主对Friend白血病病毒的限制；输入病毒粒子RNA的命运
Cell. 1974 Aug;2(4):271-7. doi: 10.1016/0092-8674(74)90021-x.
6
Comparison of immature (rapid harvest) and mature Rous sarcoma virus particles.未成熟（快速收获）的劳斯肉瘤病毒颗粒与成熟劳斯肉瘤病毒颗粒的比较。
Virology. 1972 Dec;50(3):851-64. doi: 10.1016/0042-6822(72)90439-4.
7
Virus recovery in chicken cells tested with Rous sarcoma cell DNA.用劳氏肉瘤细胞DNA在鸡细胞中进行病毒复苏。
Nat New Biol. 1972 May 10;237(71):35-9. doi: 10.1038/newbio237035a0.
8
Ribonucleic acid directed deoxyribonucleic acid synthesis by the purified deoxyribonucleic acid polymerase of Rous sarcoma virus. Characterization of the enzymatic product.劳斯肉瘤病毒纯化的脱氧核糖核酸聚合酶催化的核糖核酸指导的脱氧核糖核酸合成。酶促产物的特性
Biochemistry. 1972 Jun 6;11(12):2343-51. doi: 10.1021/bi00762a021.
9
RNA-dependent DNA polymerase activity of RNA tumor viruses. II. Directing influence of RNA in the reaction.RNA肿瘤病毒的RNA依赖性DNA聚合酶活性。II. 反应中RNA的直接导向作用。
J Virol. 1972 Jan;9(1):130-42. doi: 10.1128/JVI.9.1.130-142.1972.
10
RNA-dependent DNA polymerase activity of RNA tumor viruses. I. Directing influence of DNA in the reaction.RNA肿瘤病毒的RNA依赖性DNA聚合酶活性。I. 反应中DNA的直接影响。
J Virol. 1972 Jan;9(1):116-29. doi: 10.1128/JVI.9.1.116-129.1972.
Zotero 插件