新生仔猪血清中免疫球蛋白IgG、IgA和IgM的半衰期。
Half-lives of immunoglobulins IgG, IgA and IgM in the serum of new-born pigs.
作者信息
Curtis J, Bourne F J
出版信息
Immunology. 1973 Jan;24(1):147-55.
Abstract
Half-lives of immunoglobulins IgA, IgG and IgM labelled with Iodine-125 were measured and compared with the half-lives of these immunoglobulins calculated from plasma levels during the first 2–3 weeks of life. The two methods gave similar results for IgG and IgA, but the mean IgM half-life calculated from plasma IgM levels was significantly longer than the mean half-life of IgM-I. IgM production and passage into the circulatory system during the first week of life could account for this difference.
摘要
测量了用碘 - 125标记的免疫球蛋白IgA、IgG和IgM的半衰期，并与根据出生后前2 - 3周血浆水平计算出的这些免疫球蛋白的半衰期进行了比较。对于IgG和IgA，两种方法得出的结果相似，但根据血浆IgM水平计算出的IgM平均半衰期明显长于IgM - I的平均半衰期。出生后第一周IgM的产生及其进入循环系统的过程可以解释这种差异。
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