基因选择的高反应和低反应小鼠品系中的狂犬病病毒免疫力。
Rabies virus immunity in genetically selected high- and low-responder lines of mice.
作者信息
Nilsson M R, Sant'anna O A, Siqueira M, Nilsson T T, Gennari M
出版信息
Infect Immun. 1979 Jul;25(1):23-6. doi: 10.1128/iai.25.1.23-26.1979.
Abstract
The antibody responsiveness to and the specific vaccination effect of rabies virus infection were investigated in high- and low-responder lines of mice produced by two-way selective breedings for quantitative production of antibodies to flagellar (H/f and L/f lines) or somatic (H/s and L/s lines) antigens of salmonellae. After specific immunization, both high lines were more resistant to rabies virus infection than were the low lines, and the protector effect was related to the level of antibody produced, as demonstrated by neutralizing serum activity. The present findings confirm the nonspecific genetic modification of the general antibody responsiveness induced in high- and low-responder lines selected for quantitative antibody production.
摘要
通过对沙门氏菌鞭毛（H/f和L/f系）或菌体（H/s和L/s系）抗原抗体定量产生进行双向选择育种培育出的高应答和低应答品系小鼠，研究了其对狂犬病病毒感染的抗体反应性及特异性疫苗接种效果。特异性免疫后，两个高应答品系小鼠比低应答品系小鼠对狂犬病病毒感染更具抵抗力，且保护作用与产生的抗体水平相关，这通过血清中和活性得以证明。目前的研究结果证实了在为抗体定量产生而选择的高应答和低应答品系中诱导的一般抗体反应性的非特异性基因修饰。
相似文献
1
Rabies virus immunity in genetically selected high- and low-responder lines of mice.基因选择的高反应和低反应小鼠品系中的狂犬病病毒免疫力。
Infect Immun. 1979 Jul;25(1):23-6. doi: 10.1128/iai.25.1.23-26.1979.
2
Polygenic control of antibody production and correlation with vaccine induced resistance to rabies virus in high and low antibody responder mice.高、低抗体应答小鼠中抗体产生的多基因控制及其与疫苗诱导的抗狂犬病病毒抗性的相关性。
Arch Virol. 1996;141(8):1397-406. doi: 10.1007/BF01718243.
3
Kinetics of different specific immunological parameters after rabies vaccination in mice.小鼠接种狂犬病疫苗后不同特异性免疫参数的动力学
Infect Immun. 1979 Jun;24(3):600-5. doi: 10.1128/iai.24.3.600-605.1979.
4
Duration of immunity: an anamnestic response 14 years after rabies vaccination with purified chick embryo cell rabies vaccine.免疫持续时间：使用纯化鸡胚细胞狂犬病疫苗接种狂犬病14年后的回忆应答。
J Travel Med. 2007 Jan-Feb;14(1):63-4. doi: 10.1111/j.1708-8305.2006.00097.x.
5
Cell mediated immune response in canine antirabies vaccination.
Rev Inst Med Trop Sao Paulo. 1985 Jan-Feb;27(1):1-5. doi: 10.1590/s0036-46651985000100001.
6
Immunity against the European bat rabies (Duvenhage) virus induced by rabies vaccines: an experimental study in mice.狂犬病疫苗诱导的针对欧洲蝙蝠狂犬病（杜文黑格）病毒的免疫：小鼠实验研究
Vaccine. 1988 Aug;6(4):362-8. doi: 10.1016/0264-410x(88)90184-3.
7
Genetic control of serum neutralizing-antibody response to rabies vaccination and survival after a rabies challenge infection in mice.小鼠接种狂犬病疫苗后血清中和抗体反应及狂犬病攻击感染后存活情况的遗传控制
J Virol. 1986 Jul;59(1):98-102. doi: 10.1128/JVI.59.1.98-102.1986.
8
Protective efficacy in mice of post-exposure vaccination with vaccinia virus recombinant expressing either rabies virus glycoprotein or nucleoprotein.用表达狂犬病病毒糖蛋白或核蛋白的痘苗病毒重组体进行暴露后接种在小鼠中的保护效力。
J Gen Virol. 1994 Jun;75 ( Pt 6):1339-44. doi: 10.1099/0022-1317-75-6-1339.
9
Adult dogs receiving a rabies booster dose with a recombinant adenovirus expressing rabies virus glycoprotein develop high titers of neutralizing antibodies.接受用表达狂犬病病毒糖蛋白的重组腺病毒进行狂犬病加强剂量接种的成年犬会产生高滴度的中和抗体。
Vaccine. 2000 Jun 15;18(25):2804-7. doi: 10.1016/s0264-410x(00)00088-8.
10
Rabies antibody titres in vaccinated reindeer.
Acta Vet Scand. 1993;34(2):199-202. doi: 10.1186/BF03548210.
引用本文的文献
1
Antibody responsiveness during immunization and challenge of genetically modified antibody responder mice with murine hepatitis virus 3.在对基因改造的抗体反应小鼠进行免疫接种并用鼠肝炎病毒3进行攻击期间的抗体反应性。
Immunobiology. 2003;207(4):275-83. doi: 10.1078/0171-2985-00239.
2
Differences between C57BL/6 and BALB/cBy mice in mortality and virus replication after intranasal infection with neuroadapted Sindbis virus.神经适应型辛德毕斯病毒鼻内感染后，C57BL/6小鼠和BALB/cBy小鼠在死亡率和病毒复制方面的差异。
J Virol. 2000 Jul;74(13):6156-61. doi: 10.1128/jvi.74.13.6156-6161.2000.
3
Polygenic control of antibody production and correlation with vaccine induced resistance to rabies virus in high and low antibody responder mice.高、低抗体应答小鼠中抗体产生的多基因控制及其与疫苗诱导的抗狂犬病病毒抗性的相关性。
Arch Virol. 1996;141(8):1397-406. doi: 10.1007/BF01718243.
4
A genetic analysis of macrophage activation and specific antibodies in relation to the resistance of heterogeneous mouse populations to MHV3 infection.关于异质小鼠群体对MHV3感染的抗性，巨噬细胞激活和特异性抗体的遗传分析。
Arch Virol. 1994;139(3-4):417-25. doi: 10.1007/BF01310802.
5
Murine resistance to street rabies virus: genetic analysis by testing second-backcross progeny and verification of allelic resistance genes in SJL/J and CBA/J mice.小鼠对街狂犬病毒的抗性：通过检测第二代回交后代进行遗传分析，并在SJL/J和CBA/J小鼠中验证等位抗性基因
J Virol. 1984 May;50(2):359-62. doi: 10.1128/JVI.50.2.359-362.1984.
6
Pathogenesis of street rabies virus infections in resistant and susceptible strains of mice.狂犬病毒街毒株在抗性和易感小鼠品系中的致病机制。
J Virol. 1985 Sep;55(3):788-95. doi: 10.1128/JVI.55.3.788-795.1985.
7
Genetic control of serum neutralizing-antibody response to rabies vaccination and survival after a rabies challenge infection in mice.小鼠接种狂犬病疫苗后血清中和抗体反应及狂犬病攻击感染后存活情况的遗传控制
J Virol. 1986 Jul;59(1):98-102. doi: 10.1128/JVI.59.1.98-102.1986.
8
Role of CD4+ and CD8+ T cells in murine resistance to street rabies virus.CD4+和CD8+ T细胞在小鼠抵抗街狂犬病毒中的作用。
J Virol. 1991 Jul;65(7):3429-34. doi: 10.1128/JVI.65.7.3429-3434.1991.
本文引用的文献
1
Precision of measurement of Lansing virus infectivity in cotton rats.棉鼠中兰辛病毒感染性测量的精度
Am J Hyg. 1952 Mar;55(2):268-75. doi: 10.1093/oxfordjournals.aje.a119520.
2
[Titration of rabies antibodies practiced on human sera].
Bull Off Int Epizoot. 1967 Mar-Apr;67(3):383-7.
3
Equivalent responsiveness to branched polysaccharides and their dinitrophenyl conjugates in the Biozzi high and low responder lines of mice.
Eur J Immunol. 1974 Jul;4(7):453-7. doi: 10.1002/eji.1830040702.
4
Laboratory techniques in rabies: Habel test for potency.
Monogr Ser World Health Organ. 1973(23):276-7.
5
Laboratory techniques in rabies: suckling mouse brain vaccine.
Monogr Ser World Health Organ. 1973(23):216-20.
6
[Genetic regulation of immunoglobulin synthesis during immune response].[免疫应答期间免疫球蛋白合成的基因调控]
Ann Immunol (Paris). 1974 Jan;125C(1-2):107-42.
7
Polygenic regulation of antibody synthesis to sheep erythrocytes in the mouse: a genetic analysis.小鼠对绵羊红细胞抗体合成的多基因调控：一项遗传学分析。
Eur J Immunol. 1976 Jan;6(1):43-51. doi: 10.1002/eji.1830060110.
8
[Non-specific polygenic regulation of antibody synthesis].
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):393-9.
9
Nonspecific genetic regulation of antibody responsiveness in the mouse.
Eur J Immunol. 1977 Apr;7(4):195-203. doi: 10.1002/eji.1830070402.
Zotero 插件