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抗甲状腺球蛋白抗体在免疫球蛋白G亚类中的分布。

The distribution of anti-thyroglobulin antibodies in the immunoglobulin G subclasses.

作者信息

Hay F C, Torrigiani G

出版信息

Clin Exp Immunol. 1973 Dec;15(4):517-21.

PMID:4801364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1553963/
Abstract

Using the coprecipitation technique with rabbit antisera specific for the human IgG subclasses, the antigen–binding capacity for thyroglobulin has been investigated in patients with Hashimoto's disease. Anti-thyroglobulin activity was found in all four subclasses. The proportion of the total activity in each subclass closely paralleled the relative amounts of each subclass in normal serum.

摘要

利用针对人IgG亚类的兔抗血清共沉淀技术，对桥本氏病患者甲状腺球蛋白的抗原结合能力进行了研究。在所有四个亚类中均发现了抗甲状腺球蛋白活性。每个亚类中总活性的比例与正常血清中每个亚类的相对含量密切平行。

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The distribution of anti-thyroglobulin antibodies in the immunoglobulin G subclasses.抗甲状腺球蛋白抗体在免疫球蛋白G亚类中的分布。
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引用本文的文献

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Thyroglobulin autoantibodies switch to immunoglobulin (Ig)G1 and IgG3 subclasses and preserve their restricted epitope pattern after 131I treatment for Graves' hyperthyroidism: the activity of autoimmune disease influences subclass distribution but not epitope pattern of autoantibodies.甲状腺球蛋白自身抗体在接受¹³¹I治疗Graves病甲亢后转变为免疫球蛋白（Ig）G1和IgG3亚类，并保留其受限的表位模式：自身免疫性疾病的活动影响自身抗体的亚类分布，但不影响表位模式。
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The prevalence of antithyroid autoantibodies in normal Korean population--age, sex distribution and its relation to thyroid function.韩国正常人群中抗甲状腺自身抗体的患病率——年龄、性别分布及其与甲状腺功能的关系。
Korean J Intern Med. 1986 Jan;1(1):31-6. doi: 10.3904/kjim.1986.1.1.31.
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本文引用的文献

1
Preparation of iodine-131 labelled human growth hormone of high specific activity.高比活度碘-131标记人生长激素的制备
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SEPARATION OF THYROIDAL IODOPROTEINS AND PURIFICATION OF THYROGLOBULIN BY GEL FILTRATION AND DENSITY GRADIENT CENTRIFUGATION.通过凝胶过滤和密度梯度离心法分离甲状腺碘蛋白并纯化甲状腺球蛋白
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THYROGLOBULIN ANTIBODY ACTIVITY IN THE GAMMA-GLOBULINS GAMMA-A, GAMMA-B AND GAMMA-C OF HUMAN SERUM.
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SUBCLASSES OF HUMAN GAMMA-2-GLOBULIN BASED ON DIFFERENCES IN THE HEAVY POLYPEPTIDE CHAINS.基于重多肽链差异的人γ-2球蛋白亚类
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ANTIBODY ACTIVITY IN SIX CLASSES OF HUMAN IMMUNOGLOBULINS.六类人免疫球蛋白中的抗体活性
Science. 1964 Feb 7;143(3606):588-90. doi: 10.1126/science.143.3606.588.
7
Characterization of anti-thyroglobulin factors in human serum.人血清中抗甲状腺球蛋白因子的特性分析。
J Clin Invest. 1960 Aug;39(8):1259-65. doi: 10.1172/JCI104141.
8
The determination of the molecular weight of different autoprecipitins in Hashimoto's disease by a new immunologic method.用一种新的免疫学方法测定桥本氏病中不同自身沉淀素的分子量。
J Lab Clin Med. 1959 Apr;53(4):517-24.
9
A quantitative immunochemical measure of the primary interaction between I BSA and antibody.一种对牛血清白蛋白（BSA）与抗体之间主要相互作用的定量免疫化学测定方法。
J Infect Dis. 1958 Nov-Dec;103(3):239-62. doi: 10.1093/infdis/103.3.239.
10
Studies on non-precipitating antibody coexisting with precipitating antibody. I. Production of a blocking type antibody in rabbits.与沉淀抗体共存的非沉淀抗体的研究。I. 兔体内阻断型抗体的产生。
J Immunol. 1958 Jul;81(1):14-22.