对右旋苯丙胺在固定间隔时间表下对行为影响的详细分析。
A detailed analysis of the effects of d-amphetamine on behavior under fixed-interval schedules.
作者信息
Branch M N, Gollub L R
出版信息
J Exp Anal Behav. 1974 May;21(3):519-39. doi: 10.1901/jeab.1974.21-519.
Abstract
Pigeons were exposed to fixed-interval schedules of food reinforcement with durations of 300 sec, 100 sec, or 40 sec. A range of doses of d-amphetamine was administered to each pigeon, and the resulting behavior was analyzed at several levels of detail. Average rates in different portions of the intervals predicted the magnitude of the drug's effect, but a finer analysis showed that average rates did not adequately characterize the behavior in some parts of the intervals. The probability of responding in different parts of an interval without drug was also a good predictor of the magnitude of the effect of d-amphetamine, and at the same time was more descriptive of the interval-to-interval performance. Analyses of the control performance indicated that responding in individual intervals could be described as consisting of two parts: a very low, or zero, rate at the beginning of the interval followed by an abrupt transition to a slightly, but reliably, positively accelerated rate maintained until reinforcement.
摘要
鸽子被置于时长为300秒、100秒或40秒的固定间隔食物强化时间表下。给每只鸽子施用一系列剂量的右旋苯丙胺，并对由此产生的行为进行了多个层面的详细分析。间隔不同部分的平均反应率预测了药物效应的大小，但更精细的分析表明，平均反应率并不能充分描述间隔某些部分的行为。在无药物情况下间隔不同部分的反应概率也是右旋苯丙胺效应大小的良好预测指标，同时更能描述间隔间的表现。对照表现的分析表明，单个间隔内的反应可描述为由两部分组成：间隔开始时极低或为零的反应率，随后突然转变为轻微但可靠的正加速反应率，并持续到强化。
相似文献
1
A detailed analysis of the effects of d-amphetamine on behavior under fixed-interval schedules.对右旋苯丙胺在固定间隔时间表下对行为影响的详细分析。
J Exp Anal Behav. 1974 May;21(3):519-39. doi: 10.1901/jeab.1974.21-519.
2
Pentobarbital and d-amphetamine effects on concurrent performances.戊巴比妥和右旋苯丙胺对同时进行的行为表现的影响。
J Exp Anal Behav. 1979 Jan;31(1):141-58. doi: 10.1901/jeab.1979.31-141.
3
Effects of cocaine and d-amphetamine on behavior maintained under various schedules of food presentation in squirrel monkeys.可卡因和右旋苯丙胺对松鼠猴在不同食物呈现时间表下维持的行为的影响。
J Pharmacol Exp Ther. 1977 Apr;201(1):33-43.
4
Conjunctive schedules of reinforcement. I. Rate-dependent effects of pentobarbital and d-amphetamine.强化的联合程序。I. 戊巴比妥和右旋苯丙胺的速率依赖性效应。
J Exp Anal Behav. 1974 Nov;22(3):561-73. doi: 10.1901/jeab.1974.22-561.
5
Drugs and punished responding. II. d-Amphetamine-induced increases in punished responding.药物与受罚反应。II. 右旋苯丙胺引起的受罚反应增加。
J Exp Anal Behav. 1973 Sep;20(2):291-300. doi: 10.1901/jeab.1973.20-291.
6
Some effects of delta-amphetamine and pentobarbital on performance under a long fixed-interval schedule.δ-苯丙胺和戊巴比妥对长固定间隔时间表下行为表现的一些影响。
J Exp Anal Behav. 1976 May;25(3):389-99. doi: 10.1901/jeab.1976.25-389.
7
Molecular analyses of the effects of d-amphetamine on fixed-interval schedule performances of rats.右旋苯丙胺对大鼠固定间隔时间表行为影响的分子分析。
J Exp Anal Behav. 1986 Mar;45(2):207-19. doi: 10.1901/jeab.1986.45-207.
8
Effects of d-amphetamine on responding under second-order schedules of reinforcement with paired and nonpaired brief stimuli.右旋苯丙胺对在伴有配对和非配对简短刺激的二级强化程序下反应的影响。
J Exp Anal Behav. 1991 Sep;56(2):289-302. doi: 10.1901/jeab.1991.56-289.
9
Effects of d-amphetamine on performance under several parameters of multiple fixed-ratio, fixed-interval schedules.右旋苯丙胺对多种固定比率、固定间隔时间表的多个参数下的行为表现的影响。
J Pharmacol Exp Ther. 1969 May;167(1):26-33.
10
Response suppression by visual stimuli paired with postsession d-amphetamine injections in the pigeon.鸽子中与会话后注射右旋苯丙胺配对的视觉刺激对反应的抑制作用。
J Exp Anal Behav. 1983 Jan;39(1):165-73. doi: 10.1901/jeab.1983.39-165.
引用本文的文献
1
Rate-dependent drug effects: History and contemporary implications.速率依赖性药物效应：历史与当代意义
J Pharmacol Exp Ther. 2025 May;392(5):103575. doi: 10.1016/j.jpet.2025.103575. Epub 2025 Apr 7.
2
Cisplatin decreases voluntary wheel-running activity but does not impair food-motivated behavior in mice.顺铂可减少小鼠的自发转轮活动，但不损害其食物动机行为。
Brain Behav Immun. 2023 Jul;111:169-176. doi: 10.1016/j.bbi.2023.04.006. Epub 2023 Apr 17.
3
Development of key-pecking, pause, and ambulation during extended exposure to a fixed-interval schedule of reinforcement.在固定间隔强化程序的长时间暴露下，关键啄食、停顿和行走的发展。
J Exp Anal Behav. 2012 May;97(3):333-46. doi: 10.1901/jeab.2012.97-333.
4
The good, the bad, and the aggregate.善、恶与总量。
Behav Anal. 2000 Spring;23(1):107-15. doi: 10.1007/BF03392005.
5
Temporal control in fixed-interval schedules.固定时距程序中的时间控制。
J Exp Anal Behav. 1994 Jan;61(1):1-9. doi: 10.1901/jeab.1994.61-1.
6
The microanalysis of fixed-interval responding.固定间隔反应的微分析。
J Exp Anal Behav. 1983 Mar;39(2):327-43. doi: 10.1901/jeab.1983.39-327.
7
Responding maintained under intermittent schedules of electric-shock presentation: "Safety" or schedule effects?在间歇性电击呈现的条件下维持反应：“安全”还是程序效应？
J Exp Anal Behav. 1981 Sep;36(2):171-90. doi: 10.1901/jeab.1981.36-171.
8
Responding under sequence schedules of electric shock presentation.对电击呈现的序列时间表做出反应。
J Exp Anal Behav. 1981 May;35(3):323-34. doi: 10.1901/jeab.1981.35-323.
9
Effects of instructional constraints on human fixed-interval performance.指导约束对人类固定时距表现的影响。
J Exp Anal Behav. 1981 Mar;35(2):217-25. doi: 10.1901/jeab.1981.35-217.
10
Temporal control of behavior: schedule interactions.行为的时间控制：时间表相互作用。
J Exp Anal Behav. 1978 Nov;30(3):255-70. doi: 10.1901/jeab.1978.30-255.
本文引用的文献
1
Responding under discrete-trial fixed-interval schedules of reinforcement.在离散试验固定间隔强化程序下做出反应。
J Exp Anal Behav. 1972 Sep;18(2):187-99. doi: 10.1901/jeab.1972.18-187.
2
Changing the response unit from a single peck to a fixed number of pecks in fixed-interval schedules.将反应单位从单次啄食改为固定间隔时间内的固定啄食次数。
J Exp Anal Behav. 1972 Mar;17(2):193-200. doi: 10.1901/jeab.1972.17-193.
3
Sequential patterns in post-reinforcement pauses on fixed-interval schedules of food.固定时距食物强化程序中强化后停顿的序列模式。
J Exp Anal Behav. 1971 Mar;15(2):221-31. doi: 10.1901/jeab.1971.15-221.
4
The response-reinforcement dependency in fixed-interval schedules of reinforcement.固定间隔强化程序中的反应-强化依存关系。
J Exp Anal Behav. 1970 Jul;14(1):55-60. doi: 10.1901/jeab.1970.14-55.
5
Interresponse time duration in fixed-interval schedules of reinforcement: control by ordinal position and time since reinforcement.固定间隔强化程序中的反应时持续时间：由顺序位置和强化后时间控制。
J Exp Anal Behav. 1970 Jul;14(1):49-53. doi: 10.1901/jeab.1970.14-49.
6
A two-state analysis of fixed-interval responding in the pigeon.鸽子固定时距反应的两状态分析。
J Exp Anal Behav. 1969 Sep;12(5):677-87. doi: 10.1901/jeab.1969.12-677.
7
Reinforcement frequency and contingency as factors in fixed-ratio behavior.强化频率和关联性作为固定比率行为的因素。
J Exp Anal Behav. 1969 May;12(3):391-5. doi: 10.1901/jeab.1969.12-391.
8
Are theories of learning necessary?学习理论是必要的吗？
Psychol Rev. 1950 Jul;57(4):193-216. doi: 10.1037/h0054367.
9
A BEHAVIORAL EFFECT OF AMOBARBITAL.异戊巴比妥的一种行为效应。
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1964 Jun 22;248:296-307. doi: 10.1007/BF00246347.
10
A mathematical index of performance on fixed-interval schedules of reinforcement.固定间隔强化程序表上表现的数学指标。
J Exp Anal Behav. 1960 Jul;3(3):193-9. doi: 10.1901/jeab.1960.3-193.
Zotero 插件