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大肠杆菌素E1和K对大肠杆菌的作用与烈性噬菌体流产感染效应的比较。

Comparison of the action of colicins E1 and K on Escherichia coli with the effects of abortive infection by virulent bacteriophages.

作者信息

Fields K L

出版信息

J Bacteriol. 1969 Jan;97(1):78-82. doi: 10.1128/jb.97.1.78-82.1969.

Abstract

Abortive infection of certain strains of Escherichia coli or Shigella dysenteriae with phages of the T-even group or with phage T5 resembles the action of colicin E1 or K on sensitive bacteria, especially in the effects on biosynthetic processes. Tests on transport systems and on adenosine triphosphate levels suggest, however, that different mechanisms are involved in the two cases. Abortive infection appears to cause damage to the permeability barrier of the cell, whereas the colicins interfere more directly with the energy metabolism of the bacteria.

摘要

用 T 偶数群噬菌体或噬菌体 T5 对某些大肠杆菌或痢疾志贺氏菌菌株进行流产感染,类似于大肠杆菌素 E1 或 K 对敏感细菌的作用,特别是在对生物合成过程的影响方面。然而,对转运系统和三磷酸腺苷水平的测试表明,这两种情况涉及不同的机制。流产感染似乎会对细胞的渗透屏障造成损害,而大肠杆菌素则更直接地干扰细菌的能量代谢。

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