兔细胞介导免疫和移植免疫中的细胞。I. 骨髓抗原反应性细胞不参与移植排斥反应。
Cells involved in cell-mediated and transplantation immunity in the rabbit. I. The noninvolvement of the bone marrow antigen reactive cell in the transplant rejection reaction.
作者信息
Richter M, Abdou N I, Midgley R D
出版信息
Proc Natl Acad Sci U S A. 1970 Jan;65(1):70-3. doi: 10.1073/pnas.65.1.70.
Abstract
Rabbits were subjected to 800 r total body irradiation to render them immunoincopetent with respect to the humoral immune response. These rabbits were, however, only slightly less capable of rejecting skin allografts than nonirradiated rabbits. Furthermore, the administration of normal or specifically "primed" bone marrow cells (bone marrow obtained from a rabbit injected one to two days previously with the spleen cells obtained from the prospective skin donor) did not enhance or inhibit the graft rejection reaction. It is concluded that the cells mediating the humoral immune response are different from those mediating the cellular immune response.
摘要
对兔子进行800伦琴的全身照射，以使它们在体液免疫反应方面免疫无能。然而，这些兔子排斥同种异体皮肤移植的能力仅比未受照射的兔子略低。此外，给予正常的或经过特殊“致敏”的骨髓细胞（从一只在一到两天前注射了预期皮肤供体的脾细胞的兔子身上获取的骨髓）并没有增强或抑制移植排斥反应。得出的结论是，介导体液免疫反应的细胞与介导细胞免疫反应的细胞不同。
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Cells involved in cell-mediated and transplantation immunity in the rabbit. I. The noninvolvement of the bone marrow antigen reactive cell in the transplant rejection reaction.兔细胞介导免疫和移植免疫中的细胞。I. 骨髓抗原反应性细胞不参与移植排斥反应。
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本文引用的文献
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Cells involved in the immune response. VI. The immune response to red blood cells in irradiated rabbits after administration of normal, primed, or immune allogeneic rabbit bone marrow cells.参与免疫反应的细胞。VI. 给受照射的兔子注射正常、致敏或免疫的同种异体兔骨髓细胞后对红细胞的免疫反应。
J Exp Med. 1969 Apr 1;129(4):757-74. doi: 10.1084/jem.129.4.757.
2
Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes.免疫反应中的细胞间相互作用。II. 给受照射小鼠输注骨髓、胸腺或胸导管淋巴细胞后溶血素形成细胞的来源。
J Exp Med. 1968 Oct 1;128(4):821-37. doi: 10.1084/jem.128.4.821.
3
Cells involved in the immune response. 8. The relationship between the loss and reappearance of antigen-reactive cells and immune responsiveness after irradiation of normal adult rabbits.参与免疫反应的细胞。8. 正常成年兔经照射后抗原反应性细胞的丧失与再现及免疫反应性之间的关系。
J Exp Med. 1969 Oct 1;130(4):867-76. doi: 10.1084/jem.130.4.867.
4
Immunocompetence of transferred thymus-marrow cell combinations.转移的胸腺-骨髓细胞组合的免疫活性。
J Immunol. 1966 Dec;97(6):828-32.
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Cells involved in the immune response, IX. Depletion from the normal rabbit bone marrow of antigen-reactive cells directed toward human peripheral leukocytes.参与免疫反应的细胞，IX. 从正常兔骨髓中清除针对人外周血白细胞的抗原反应性细胞。
Proc Natl Acad Sci U S A. 1969 Aug;63(4):1136-43. doi: 10.1073/pnas.63.4.1136.
6
Cells involved in the immune response. VII. The demonstration, using allotypic markers, of antibody formation by irradiation-resistant cells of irradiated rabbits injected with normal allogeneic bone marrow cells and sheep erythrocytes.参与免疫反应的细胞。VII. 使用同种异型标记，证明注射正常同种异体骨髓细胞和绵羊红细胞的受照射兔的抗辐射细胞形成抗体。
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Cells involved in the immune response. XV. The organ source of the antigen reactive cells in the normal rabbit.参与免疫反应的细胞。十五、正常兔体内抗原反应性细胞的器官来源。
Int Arch Allergy Appl Immunol. 1970;38(3):269-81. doi: 10.1159/000230280.
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Cells involved in the immune response. IV. The response of normal and immune rabbit bone marrow and lymphoid tissue lymphocytes to antigens in vitro.参与免疫反应的细胞。IV. 正常和免疫兔骨髓及淋巴组织淋巴细胞在体外对抗原的反应。
J Exp Med. 1968 Nov 1;128(5):1099-128. doi: 10.1084/jem.128.5.1099.
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