Wardle E N, Wright N A
Br Med J. 1970 Nov 21;4(5733):472-4. doi: 10.1136/bmj.4.5733.472.
A single dose of endotoxin given to rats with obstructive jaundice produced death with intravascular coagulation. This action was apparently due to delayed clearance of endotoxin from the circulation. The finding is relevant to "hepatorenal failure," which can be caused by bacteraemia after biliary tract operations.
给阻塞性黄疸大鼠单次注射内毒素会导致其因血管内凝血而死亡。这种作用显然是由于内毒素从循环系统中的清除延迟所致。这一发现与“肝肾衰竭”相关,后者可能由胆道手术后的菌血症引起。