大肠杆菌中的新型抑制剂。
New suppresor in Escherichia coli.
作者信息
Russell R R, Pittard A J
出版信息
J Bacteriol. 1971 Sep;107(3):736-40. doi: 10.1128/jb.107.3.736-740.1971.
Abstract
During the genetic mapping of a mutation in the pheS gene which confers temperature sensitivity on a strain of Escherichia coli K-12, an extragenic suppressor was discovered which restores ability to grow at the restrictive temperature. The suppressor, which has been named supQ, is cotransduced by bacteriophage P1 with the purE marker. SupQ does not suppress a number of amber or ochre mutations. SupQ(-) is carried by the prototrophic Hfr Hayes strain AB259, and the presence of the supQ(-) allele impairs the growth of this strain at 42 C.
摘要
在对赋予大肠杆菌K - 12菌株温度敏感性的pheS基因突变进行基因定位的过程中，发现了一种基因外抑制子，它能恢复菌株在限制温度下生长的能力。这种抑制子被命名为supQ，它与purE标记一起被噬菌体P1共转导。SupQ不能抑制许多琥珀突变或赭石突变。原养型Hfr海斯菌株AB259携带SupQ(-)，supQ(-)等位基因的存在会损害该菌株在42℃时的生长。
相似文献
1
New suppresor in Escherichia coli.大肠杆菌中的新型抑制剂。
J Bacteriol. 1971 Sep;107(3):736-40. doi: 10.1128/jb.107.3.736-740.1971.
2
Evolution of a new gene substituting for the leuD gene of Salmonella typhimurium: characterization of supQ mutations.鼠伤寒沙门氏菌亮氨酸脱氢酶基因替代新基因的进化：supQ突变的特征分析
J Bacteriol. 1974 Sep;119(3):937-51. doi: 10.1128/jb.119.3.937-951.1974.
3
Isolation and genetic analysis of a strain of Escherichia coli K-12 with an amber recA mutation.一株具有琥珀型recA突变的大肠杆菌K-12菌株的分离与遗传分析。
J Bacteriol. 1971 Jul;107(1):388-9. doi: 10.1128/jb.107.1.388-389.1971.
4
A temperature-sensitive mutant of Escherichia coli that shows enhanced misreading of UAG/A and increased efficiency for some tRNA nonsense suppressors.一种大肠杆菌的温度敏感突变体，其对UAG/A的错读增强，并且某些tRNA无义抑制子的效率提高。
Mol Gen Genet. 1984;193(1):38-45. doi: 10.1007/BF00327411.
5
A dnaB analog specified by bacteriophage P1.由噬菌体P1指定的一种dnaB类似物。
J Mol Biol. 1975 May 25;94(3):341-66. doi: 10.1016/0022-2836(75)90207-7.
6
Map location of the pcbA mutation and physiology of the mutant.pcbA突变的图谱定位及突变体的生理学特性
J Bacteriol. 1984 Apr;158(1):216-21. doi: 10.1128/jb.158.1.216-221.1984.
7
Mapping of the fabA locus for unsaturated fatty acid biosynthesis in Escherichia coli.大肠杆菌中不饱和脂肪酸生物合成的fabA基因座定位
J Bacteriol. 1972 Oct;112(1):206-11. doi: 10.1128/jb.112.1.206-211.1972.
8
Conditionally lethal amber mutations in the dnaA region of the Escherichia coli chromosome that affect chromosome replication.大肠杆菌染色体DNA A区域中影响染色体复制的条件致死性琥珀突变。
J Bacteriol. 1979 Dec;140(3):825-34. doi: 10.1128/jb.140.3.825-834.1979.
9
The gene for ribosomal protein L25 (rplY) maps at 47.3 min near nalA in Escherichia coli K-12.核糖体蛋白L25（rplY）基因位于大肠杆菌K-12中nalA附近47.3分钟处。
Mol Gen Genet. 1979 Nov;176(3):313-8. doi: 10.1007/BF00333093.
10
The kil gene of bacteriophage lambda.噬菌体λ的kil基因。
Virology. 1975 Aug;66(2):589-604. doi: 10.1016/0042-6822(75)90231-7.
引用本文的文献
1
Linkage map of Escherichia coli K-12, edition 10: the traditional map.大肠杆菌K-12连锁图谱，第10版：传统图谱。
Microbiol Mol Biol Rev. 1998 Sep;62(3):814-984. doi: 10.1128/MMBR.62.3.814-984.1998.
2
Mutants of Escherichia coli unable to make protein at 42 C.无法在42摄氏度下合成蛋白质的大肠杆菌突变体。
J Bacteriol. 1971 Nov;108(2):790-8. doi: 10.1128/jb.108.2.790-798.1971.
3
Alanyl-tRNA synthetase of Escherichia coli: genetic analysis of the structural gene and of suppressor mutations.大肠杆菌丙氨酰 - tRNA合成酶：结构基因及抑制突变的遗传分析
Mol Gen Genet. 1974;134(4):313-23. doi: 10.1007/BF00337466.
4
Linkage map of Escherichia coli strain K-12.大肠杆菌K-12菌株的连锁图谱。
Bacteriol Rev. 1972 Dec;36(4):504-24. doi: 10.1128/br.36.4.504-524.1972.
5
Mutants of Escherichia coli with temperature-sensitive lesions in membrane phospholipid synthesis: genetic analysis of glycerol-3-phosphate acyltransferase mutants.膜磷脂合成中具有温度敏感损伤的大肠杆菌突变体：甘油-3-磷酸酰基转移酶突变体的遗传分析
Mol Gen Genet. 1972;116(3):199-210. doi: 10.1007/BF00269765.
6
Genetic analysis of ribonucleic acid polymerase mutants of Bacillus subtilis.枯草芽孢杆菌核糖核酸聚合酶突变体的遗传分析。
J Bacteriol. 1973 Apr;114(1):103-13. doi: 10.1128/jb.114.1.103-113.1973.
7
Genetic and biochemical characterization of some missense mutations in the lacZ gene of Escherichia coli K-12.大肠杆菌K-12中lacZ基因一些错义突变的遗传和生化特征分析
J Bacteriol. 1976 Jun;126(3):1063-74. doi: 10.1128/jb.126.3.1063-1074.1976.
8
Recalibrated linkage map of Escherichia coli K-12.大肠杆菌K-12的重新校准连锁图谱。
Bacteriol Rev. 1976 Mar;40(1):116-67. doi: 10.1128/br.40.1.116-167.1976.
9
Salmonella typhimurium newD and Escherichia coli leuC genes code for a functional isopropylmalate isomerase in Salmonella typhimurium-Escherichia coli hybrids.鼠伤寒沙门氏菌newD基因和大肠杆菌leuC基因在鼠伤寒沙门氏菌-大肠杆菌杂交体中编码一种功能性异丙基苹果酸异构酶。
J Bacteriol. 1979 Mar;137(3):1253-62. doi: 10.1128/jb.137.3.1253-1262.1979.
10
E. coli K-12 pel mutants, which block phage lambda DNA injection, coincide with ptsM, which determines a component of a sugar transport system.大肠杆菌K-12 pel突变体可阻止λ噬菌体DNA的注入，该突变体与ptsM基因一致，ptsM基因决定了一种糖转运系统的一个组分。
Mol Gen Genet. 1978 Apr 25;161(1):1-8. doi: 10.1007/BF00266608.
本文引用的文献
1
Genetic mapping of phenylalanyl-sRNA synthetase in Escherichia coli.大肠杆菌中苯丙氨酰 - sRNA合成酶的基因定位
Science. 1967 Jul 7;157(3784):78-9. doi: 10.1126/science.157.3784.78.
2
Altered ribosomes in a suppressor strain of Escherichia coli.大肠杆菌抑制菌株中核糖体的改变。
J Mol Biol. 1966 Apr;16(2):285-301. doi: 10.1016/s0022-2836(66)80173-0.
3
Suppression.抑制
Annu Rev Microbiol. 1966;20:401-22. doi: 10.1146/annurev.mi.20.100166.002153.
4
Mapping of suppressor loci in Escherichia coli.大肠杆菌中抑制基因座的定位
J Mol Biol. 1965 Nov;14(1):153-66. doi: 10.1016/s0022-2836(65)80237-6.
5
Map positions and specificities of suppressor mutations in Escherichia coli K-12.大肠杆菌K-12中抑制突变的图谱位置和特异性
Genetics. 1965 Aug;52(2):319-40. doi: 10.1093/genetics/52.2.319.
6
Mutations affecting iron transport in Escherichia coli.影响大肠杆菌中铁运输的突变
J Bacteriol. 1970 Oct;104(1):219-26. doi: 10.1128/jb.104.1.219-226.1970.
7
Current linkage map of Escherichia coli.大肠杆菌当前的连锁图谱。
Bacteriol Rev. 1970 Jun;34(2):155-75. doi: 10.1128/br.34.2.155-175.1970.
8
Suppressors causing temperature sensitivity of growth in Escherichia coli.导致大肠杆菌生长温度敏感性的抑制因子。
Genetics. 1968 Oct;60(2):269-80. doi: 10.1093/genetics/60.2.269.
9
Bacterial genetic factors controlling the suppression of T4 phage amber mutants. I. Suppression patterns of a collection of E. coli strains.控制T4噬菌体琥珀突变体抑制作用的细菌遗传因子。I. 一组大肠杆菌菌株的抑制模式。
Mol Gen Genet. 1968;103(3):274-93. doi: 10.1007/BF00273699.
10
Missense suppression due to a genetically altered tRNA.由于基因改变的tRNA导致的错义抑制。
Cold Spring Harb Symp Quant Biol. 1966;31:487-97. doi: 10.1101/sqb.1966.031.01.063.
Zotero 插件