[纤维肉瘤大鼠血浆中组蛋白样蛋白及其他碱性蛋白的比较电泳分析]
[Comparative electrophoretic analysis of plasma histonelike proteins and other basic proteins in rats with fibrosarcoma].
作者信息
Daskalov D P, Gavazova I G
出版信息
Vopr Med Khim. 1979 Sep-Oct;25(5):528-9.
Histone-like proteins were isolated from blood plasma of rats with tumors. By polyacrylamide gel disc electrophoresis the proteins were separated into two fractions, resembling in their mobility histone fractions H1 and H2b+H2a. Basic proteins, occurring in blood plasma and used as standards (globulin, interferon, RNAase, lysozyme), were markedly distinct in their electrophoretic properties from both histone fractions and the histone-like proteins isolated from blood plasma. These histones apparently originate from nucleoproteins of blood plasma.
从患有肿瘤的大鼠血浆中分离出类组蛋白。通过聚丙烯酰胺凝胶圆盘电泳，这些蛋白质被分离成两个组分，其迁移率类似于组蛋白组分H1和H2b + H2a。血浆中存在的用作标准品的碱性蛋白质（球蛋白、干扰素、核糖核酸酶、溶菌酶）在电泳性质上与组蛋白组分以及从血浆中分离出的类组蛋白明显不同。这些组蛋白显然源自血浆核蛋白。
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