Gerdts K G, Shah V, Savage J M, Dillon M J
J Pediatr. 1979 Dec;95(6):953-8. doi: 10.1016/s0022-3476(79)80282-6.
Renal venous PRA was measured in 49 normotensive children without renal disease undergoing routine cardiac catheterization. PRA levels did not differ significantly between both renal veins and were significantly higher in the renal veins than in the IVC. There was a constant mean ratio of 1.21 between the renal veins and the IVC at low, intermediate, and high absolute PRA levels. Three patients had a renal venous PRA ratio greater than 1.4 and the highest ratio observed was 1.55. This fidning supports 1.5 as an acceptable upper limit of normality for the interpretation of renal vein PRA ratios in the investigation of patients with suspected renal hypertension. In four patients, PRA in the renal veins was significantly lower than in the IVC. The possibility of renin removal by these kidneys is discussed.
对49名接受常规心导管检查且无肾脏疾病的血压正常儿童测量了肾静脉肾素活性（PRA）。双侧肾静脉的PRA水平无显著差异，且肾静脉中的PRA水平显著高于下腔静脉（IVC）。在低、中、高绝对PRA水平时，肾静脉与IVC之间的平均比值恒定为1.21。3例患者的肾静脉PRA比值大于1.4，观察到的最高比值为1.55。这一发现支持将1.5作为在疑似肾性高血压患者调查中解释肾静脉PRA比值正常上限的可接受值。4例患者肾静脉中的PRA显著低于IVC。讨论了这些肾脏去除肾素的可能性。
