C57BL - 10J小鼠和A - J小鼠对绵羊红细胞反应的差异。
Variations in the responses of C57BL-10J and A-J mice to sheep red blood cells.
作者信息
Silver D M, McKenzie I F, Winn H J
出版信息
J Exp Med. 1972 Nov 1;136(5):1063-71. doi: 10.1084/jem.136.5.1063.
Abstract
In response to repeated injections of sheep red blood cells, C57BL/10J mice produce predominantly 19S antibody in increasingly higher amounts, while A/J mice initially produce 19S antibody and then switch to produce increasing 7S antibody titers. In an F(1) generation all mice responded like the C57BL/10J mice. Backcross data implied genetic control involving at least three loci.
摘要
针对反复注射绵羊红细胞的情况，C57BL/10J小鼠主要产生数量越来越多的19S抗体，而A/J小鼠最初产生19S抗体，然后转而产生不断增加的7S抗体效价。在F(1)代中，所有小鼠的反应都与C57BL/10J小鼠相似。回交数据表明遗传控制涉及至少三个基因座。
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