在 pertenue 密螺旋体研究中使用叙利亚仓鼠。 （注：这里CB hamsters疑为Syrian hamsters即叙利亚仓鼠的错误表述，若按照正确表述翻译则是上述译文，若按照原文错误表述则是“在 pertenue 密螺旋体研究中使用CB仓鼠” ）
Use of CB hamsters in the study of Treponema pertenue.
作者信息
Schell R F, Le Frock J L, Babu J P, Chan J K
出版信息
Br J Vener Dis. 1979 Oct;55(5):316-9. doi: 10.1136/sti.55.5.316.
Abstract
The CB/Ss LAK strain of inbred hamster was used as a model for studies of infection with Treponema pertenue and of acquired resistance to it. When infected, this strain developed cutaneous lesions which lasted for six to seven months, even in the presence of peak titres of antitreponemal antibody. The rate of appearance and resolution of these lesions varied with the size of the inoculum. The infected hamsters' inguinal lymph nodes increased significantly in weight and teemed with treponemes for several weeks. Animals infected for eight or 10 weeks obtained quick resolution of their lesions by treatment with penicillin and were thereafter resistant to reinfection.
摘要
近交系仓鼠CB/Ss LAK品系被用作研究感染雅司螺旋体及获得性抗该螺旋体感染的模型。感染后，该品系会出现持续6至7个月的皮肤病变，即使在抗螺旋体抗体滴度达到峰值时也是如此。这些病变出现和消退的速度因接种物大小而异。受感染仓鼠的腹股沟淋巴结重量显著增加，且在数周内充满螺旋体。感染8周或10周的动物经青霉素治疗后病变迅速消退，此后对再感染具有抵抗力。
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