新生儿红斑狼疮

Neonatal lupus erythematosus.

作者信息

Draznin T H, Esterly N B, Furey N L, DeBofsky H

出版信息

J Am Acad Dermatol. 1979 Nov;1(5):437-42. doi: 10.1016/s0190-9622(79)70036-3.

PMID:512088

Abstract

The infant of a mother with systemic lupus erythematosus (SLE) developed an extensive cutaneous eruption at 5 weeks of age. Biopsy findings were consistent with cutaneous lupus erythematosus (LE). Splenomegaly, anemia, neutropenia, and depressed total hemolytic complemtnt levels were additional findings. The course was benign, and all manifestations disappeared by 4 months of age. Fifty-two previously reported infants with cutaneous lesions, congenital atrioventricular heart block, or hematologic manifestations of neonatal LE are reviewed.

摘要

一位患有系统性红斑狼疮（SLE）的母亲所生的婴儿在5周龄时出现了广泛的皮肤疹。活检结果与皮肤型红斑狼疮（LE）相符。脾肿大、贫血、中性粒细胞减少以及总溶血补体水平降低是其他发现。病程呈良性，所有症状在4月龄时消失。本文回顾了先前报道的52例患有皮肤病变、先天性房室传导阻滞或新生儿LE血液学表现的婴儿。