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男性长时间体育锻炼期间睾丸和肾上腺雄激素的血浆变化

Plasma variations in testicular and adrenal androgens during prolonged physical exercise in man.

作者信息

Morville R, Pesquies P C, Guezennec C Y, Serrurier B D, Guignard M

出版信息

Ann Endocrinol (Paris). 1979;40(5):501-10.

PMID:518032
Abstract

The evolution of the relationship between cortisol and testicular androgens was verified on two teams of respectively 10 and 9 male subjects (average age 34) running 100 km races in an average time of 14 hours. When compared to a control population of the same age, these trained athletes exhibited reduced testicular androgen levels (T and DHT) and increased adrenal androgen (delta 4) and cortisol levels with no significant alteration of LH. The period of recovery is characterized by rapid return to normal of the hormonal parameters whereas testosterone levels continue to increase in the following days. This hormonal picture, which reappears under certain pathological situations or when subjects are exposed to heavy stresses, seems to prove that the testicular androgens could be, both by their metabolic and psychic action, one of the limiting factors of physical aptitude to sustained effort.

摘要

在两组分别为10名和9名男性受试者(平均年龄34岁)中,验证了皮质醇与睾丸雄激素之间关系的演变情况,这些受试者参加了100公里赛跑,平均用时14小时。与相同年龄的对照人群相比,这些训练有素的运动员睾丸雄激素水平(睾酮和双氢睾酮)降低,肾上腺雄激素(△4)和皮质醇水平升高,促黄体生成素无显著变化。恢复期间的特征是激素参数迅速恢复正常,而睾酮水平在接下来的几天里持续升高。这种激素情况在某些病理情况下或受试者承受重压时再次出现,似乎证明睾丸雄激素可能因其代谢和心理作用,成为持续运动体能的限制因素之一。

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