肠壁囊样积气症中的呼气氢含量
Breath hydrogen in pneumatosis cystoides intestinalis.
作者信息
Gillon J, Tadesse K, Logan R F, Holt S, Sircus W
出版信息
Gut. 1979 Nov;20(11):1008-11. doi: 10.1136/gut.20.11.1008.
Abstract
Pneumatosis cystoides intestinalis (PCI) is an uncommon condition of unknown aetiology. Bacterial gas production may be an important aetiological factor, but experimental evidence in humans has been lacking. We have studied breath hydrogen excretion as an index of bacterial gas production in 12 patients with PCI and have shown that four out of five with demonstrable cysts produced unusually high levels of hydrogen while fasting. This abnormality has not been previously reported. One patient showed resolution of PCI after antibiotic treatment. These findings confirm the importance of bacterial gas production in the pathogenesis of PCI.
摘要
肠气囊肿症（PCI）是一种病因不明的罕见病症。细菌产气可能是一个重要的病因因素，但一直缺乏人体实验证据。我们研究了12例PCI患者的呼气氢排泄情况，以此作为细菌产气的指标，结果显示，在五例可证实有囊肿的患者中，有四例在禁食时产生的氢气水平异常高。此前尚未报道过这种异常情况。一名患者在接受抗生素治疗后PCI症状得到缓解。这些发现证实了细菌产气在PCI发病机制中的重要性。
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