Arita I, Henderson D A
Bull World Health Organ. 1968;39(2):277-83.
In considering global eradication of smallpox the absence of an animal reservoir is important. Present knowledge of experimental infection of non-human primates with variola virus and of a related virus infection in monkeys, termed monkeypox, is examined.From the literature review and the results of a survey of captive monkeys in 26 major biological institutions it is concluded that outbreaks of supposed smallpox and monkeypox are not frequent and that man may be comparatively insusceptible to monkeypox. A natural reservoir of smallpox in non-human primates is thought to be unlikely although further studies are warranted since the survey reveals that certain species of monkeys can be infected with smallpox and that infected monkeys can transmit infection to others.
在考虑全球根除天花时,没有动物储存宿主很重要。本文研究了目前关于用天花病毒对非人类灵长类动物进行实验性感染以及猴子中一种相关病毒感染(称为猴痘)的知识。通过文献综述以及对26家主要生物机构圈养猴子的调查结果得出结论:所谓的天花和猴痘疫情并不常见,而且人类可能对猴痘相对不易感。虽然进一步的研究是必要的,因为调查显示某些种类的猴子可感染天花且受感染的猴子能将感染传播给其他猴子,但非人类灵长类动物作为天花的自然储存宿主被认为不太可能。