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使用重症肌无力患者血清和正常对照血清对骨骼肌进行免疫荧光染色模式。

Immunofluorescence staining patterns in skeletal muscle using serum of myasthenic patients and normal controls.

作者信息

Vetters J M

出版信息

Immunology. 1965 Jul;9(1):93-5.

PMID:5320258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1423562/
Abstract

Using indirect immunofluorescent tests upon the sera of patients with myasthenia gravis and of normal subjects, two types of staining pattern are found. The first, A band staining, is seen only with myasthenic sera. The second, or I band' pattern has not previously been described and is seen in an equal proportion of normal controls and of myasthenic patients. I band' staining is a possible source of confusion in immunofluorescent tests for muscle antibody.

摘要

通过对重症肌无力患者和正常受试者的血清进行间接免疫荧光检测,发现了两种染色模式。第一种,A带染色,仅在重症肌无力患者的血清中可见。第二种,即“I带”模式,此前尚未被描述过,在正常对照组和重症肌无力患者中出现的比例相同。“I带”染色可能会在肌肉抗体的免疫荧光检测中造成混淆。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d95/1423562/41e5de371a74/immunology00426-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d95/1423562/41e5de371a74/immunology00426-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d95/1423562/41e5de371a74/immunology00426-0109-a.jpg

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Immunology. 1965 Jul;9(1):93-5.
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引用本文的文献

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本文引用的文献

1
TANNED-CELL HEMAGGLUTINATION TEST FOR DETECTION OF ANTIBODIES IN SERA OF PATIENTS WITH MYASTHENIA GRAVIS.用于检测重症肌无力患者血清中抗体的鞣酸细胞血凝试验
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Changes in serum complement activity in patients with myasthenia gravis.重症肌无力患者血清补体活性的变化
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Antiglobulin consumption test with sera from patients with myasthenia gravis.用重症肌无力患者血清进行抗球蛋白消耗试验。
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Thymic B lymphocyte clones from patients with myasthenia gravis secrete monoclonal striational autoantibodies reacting with myosin, alpha actinin, or actin.重症肌无力患者的胸腺B淋巴细胞克隆可分泌与肌球蛋白、α辅肌动蛋白或肌动蛋白发生反应的单克隆横纹肌自身抗体。
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Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin.重症肌无力合并胸腺瘤的患者血清中存在抗肌联蛋白的IgG自身抗体。
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Molecular cloning and preliminary characterization of a novel cytoplasmic antigen recognized by myasthenia gravis sera.重症肌无力血清识别的一种新型细胞质抗原的分子克隆及初步鉴定
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