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胆红素几何光异构体之间光化学相互转化的动力学

Kinetics of the photochemical interconversion among geometric photoisomers of bilirubin.

作者信息

Isobe K, Onishi S

出版信息

Biochem J. 1981 Mar 1;193(3):1029-31. doi: 10.1042/bj1931029.

DOI:10.1042/bj1931029
PMID:7305954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1162702/
Abstract

Kinetic study of the photochemical interconversion of three geometric photoisomers of bilirubin, namely peaks 1, 2 and 3, under anaerobic conditions was performed by using high-pressure liquid chromatography. Rapid and definite interconversion among these three peaks and the parent pigment occurred on radiation by blue light.

摘要

在厌氧条件下，利用高压液相色谱法对胆红素的三种几何光异构体（即峰1、峰2和峰3）的光化学相互转化进行了动力学研究。这三个峰与母体色素之间在蓝光照射下会快速且明确地发生相互转化。

相似文献

1
Kinetics of the photochemical interconversion among geometric photoisomers of bilirubin.胆红素几何光异构体之间光化学相互转化的动力学
Biochem J. 1981 Mar 1;193(3):1029-31. doi: 10.1042/bj1931029.
2
Kinetic study of photochemical and thermal conversion of bilirubin IX alpha and its photoproducts.胆红素IXα及其光产物的光化学和热转化动力学研究
Biochem J. 1983 Mar 1;209(3):695-700. doi: 10.1042/bj2090695.
3
Comparison of kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin with that bound to rat serum albumin.与结合大鼠血清白蛋白的(ZZ)-胆红素IXα的光化学变化动力学研究的比较，该(ZZ)-胆红素IXα与人血清白蛋白结合。
Biochem J. 1985 Sep 15;230(3):561-7. doi: 10.1042/bj2300561.
4
Wavelength-dependence of the relative rate constants for the main geometric and structural photoisomerization of bilirubin IX alpha bound to human serum albumin. Demonstration of green light at 510 nm as the most effective wavelength in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha via (EZ)-bilirubin.与人类血清白蛋白结合的胆红素IXα主要几何和结构光异构化的相对速率常数的波长依赖性。证明510nm的绿光作为通过（EZ）-胆红素将（ZZ）-胆红素IXα光化学转变为（EZ）-环胆红素IXα的最有效波长。
Biochem J. 1986 May 15;236(1):23-9. doi: 10.1042/bj2360023.
5
Reactivity of bilirubin photoisomers on the measurement of direct bilirubin using vanadic acid method.胆红素光异构体对钒酸法测定直接胆红素的影响
Ann Clin Biochem. 2018 Mar;55(2):296-298. doi: 10.1177/0004563217709844. Epub 2017 Jun 29.
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Significance of the endo-vinyl group of bilirubin in photochemical reactions.胆红素的内乙烯基在光化学反应中的意义。
Biochem J. 1984 Jun 1;220(2):377-83. doi: 10.1042/bj2200377.
7
Accurate and sensitive high-performance liquid chromatographic method for geometrical and structural photoisomers of bilirubin IX alpha using the relative molar absorptivity values.一种利用相对摩尔吸光系数值测定胆红素IXα几何和结构光异构体的准确且灵敏的高效液相色谱法。
J Chromatogr A. 1999 Jul 2;848(1-2):169-77. doi: 10.1016/s0021-9673(99)00469-0.
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Wavelength dependence of the geometric and structural photoisomerization of bilirubin bound to human serum albumin.与人类血清白蛋白结合的胆红素的几何和结构光异构化的波长依赖性。
Biol Neonate. 1987;51(1):10-7. doi: 10.1159/000242625.
9
Change of bilirubin photoisomers in the urine and serum before and after phototherapy compared with light source.光疗前后尿液和血清中胆红素光异构体的变化与光源的比较。
Pediatr Int. 2004 Dec;46(6):640-4. doi: 10.1111/j.1442-200x.2004.01973.x.
10
Kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin. Demonstration of (EZ)-bilirubin IX alpha as an intermediate in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha.与人类血清白蛋白结合的（ZZ）-胆红素IXα光化学变化的动力学研究。证明（EZ）-胆红素IXα是（ZZ）-胆红素IXα向（EZ）-环胆红素IXα光化学变化过程中的中间体。
Biochem J. 1985 Feb 15;226(1):251-8. doi: 10.1042/bj2260251.

引用本文的文献

1
Fetal and neonatal bilirubin metabolism.胎儿及新生儿胆红素代谢
Front Pediatr. 2023 Feb 7;10:1002408. doi: 10.3389/fped.2022.1002408. eCollection 2022.
2
Noninvasive monitoring of bilirubin photoisomer excretion during phototherapy.光疗期间胆红素光异构体排泄的无创监测。
Sci Rep. 2022 Jul 12;12(1):11798. doi: 10.1038/s41598-022-16180-9.
3
Kinetics of biliary excretion of the main two bilirubin photoproducts after injection into Gunn rats.注射到冈恩大鼠体内后两种主要胆红素光产物的胆汁排泄动力学。
Biochem J. 1981 Jul 15;198(1):107-12. doi: 10.1042/bj1980107.
4
Concerning the structure of photobilirubin II.关于光胆红素II的结构。
Biochem J. 1982 Jan 1;201(1):179-88. doi: 10.1042/bj2010179.
5
Kinetic study of photochemical and thermal conversion of bilirubin IX alpha and its photoproducts.胆红素IXα及其光产物的光化学和热转化动力学研究
Biochem J. 1983 Mar 1;209(3):695-700. doi: 10.1042/bj2090695.
6
Significance of the endo-vinyl group of bilirubin in photochemical reactions.胆红素的内乙烯基在光化学反应中的意义。
Biochem J. 1984 Jun 1;220(2):377-83. doi: 10.1042/bj2200377.
7
Comparison of kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin with that bound to rat serum albumin.与结合大鼠血清白蛋白的(ZZ)-胆红素IXα的光化学变化动力学研究的比较，该(ZZ)-胆红素IXα与人血清白蛋白结合。
Biochem J. 1985 Sep 15;230(3):561-7. doi: 10.1042/bj2300561.
8
Kinetic study of the photochemical changes of (ZZ)-bilirubin IX alpha bound to human serum albumin. Demonstration of (EZ)-bilirubin IX alpha as an intermediate in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha.与人类血清白蛋白结合的（ZZ）-胆红素IXα光化学变化的动力学研究。证明（EZ）-胆红素IXα是（ZZ）-胆红素IXα向（EZ）-环胆红素IXα光化学变化过程中的中间体。
Biochem J. 1985 Feb 15;226(1):251-8. doi: 10.1042/bj2260251.
9
Wavelength-dependence of the relative rate constants for the main geometric and structural photoisomerization of bilirubin IX alpha bound to human serum albumin. Demonstration of green light at 510 nm as the most effective wavelength in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha via (EZ)-bilirubin.与人类血清白蛋白结合的胆红素IXα主要几何和结构光异构化的相对速率常数的波长依赖性。证明510nm的绿光作为通过（EZ）-胆红素将（ZZ）-胆红素IXα光化学转变为（EZ）-环胆红素IXα的最有效波长。
Biochem J. 1986 May 15;236(1):23-9. doi: 10.1042/bj2360023.

本文引用的文献

1
Demonstration of a geometric isomer of bilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant and the mechanism of jaundice phototherapy.一名高胆红素血症新生儿血清中胆红素-IXα几何异构体的证实及黄疸光疗机制
Biochem J. 1980 Sep 15;190(3):533-6. doi: 10.1042/bj1900533.
2
High-pressure liquid chromatographic analysis of anaerobic photoproducts of bilirubin-IX alpha in vitro and its comparison with photoproducts in vivo.胆红素-IXα体外厌氧光产物的高压液相色谱分析及其与体内光产物的比较。
Biochem J. 1980 Sep 15;190(3):527-32. doi: 10.1042/bj1900527.
3
New concepts in phototherapy: photoisomerization of bilirubin IX alpha and potential toxic effects of light.光疗的新概念：胆红素IXα的光异构化及光的潜在毒性作用。
Pediatrics. 1980 Apr;65(4):740-50.
4
Preparation and properties of bilirubin photoisomers.胆红素光异构体的制备及性质
Biochem J. 1979 Oct 1;183(1):139-46. doi: 10.1042/bj1830139.
5
Configurational isomerization of bilirubin and the mechanism of jaundice phototherapy.胆红素的构型异构化与黄疸光疗机制
Biochem Biophys Res Commun. 1979 Jan 30;86(2):235-43. doi: 10.1016/0006-291x(79)90857-x.
6
Photobilirubin: an early bilirubin photoproduct detected by absorbance difference spectroscopy.光胆红素：一种通过吸光度差光谱检测到的早期胆红素光产物。
Proc Natl Acad Sci U S A. 1979 Jan;76(1):29-32. doi: 10.1073/pnas.76.1.29.