Bassili W R, Stewart G T
Lancet. 1976 Feb 28;1(7957):471-4. doi: 10.1016/s0140-6736(76)91488-4.
The general incidence of whooping-cough is lower in fully immunised children, but present immunisation schedules do not adequately protect the infant below 1 year of age either from contracting infection or from its complications. In a recent outbreak in Glasgow, nearly one-third of notified cases were fully immunised. In Glasgow and probably in the U.K. as a whole, the persistance of whooping-cough in some areas is more strongly correlated with adverse socio-economic conditions that with lack of immunisation. The decline in recent years could be attributable to improvement in these conditions at least as much as to immunisation. There is no epidemiological justification for continuing mass immunisation, but there is a strong case for an intensified eradication policy which might include selective immunisation in high-risk groups and areas.
百日咳在完全免疫的儿童中的总体发病率较低，但目前的免疫接种计划并不能充分保护1岁以下的婴儿免受感染或其并发症的影响。在格拉斯哥最近的一次疫情中，近三分之一的报告病例是完全免疫的。在格拉斯哥，可能在整个英国，百日咳在某些地区的持续存在与不利的社会经济状况的相关性比与缺乏免疫接种的相关性更强。近年来发病率的下降至少可以归因于这些状况的改善，就像归因于免疫接种一样。继续进行大规模免疫接种没有流行病学依据，但有充分理由加强根除政策，这可能包括在高危人群和地区进行选择性免疫接种。
