耐药金黄色葡萄球菌对卡那霉素的灭活与磷酸化作用
Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus.
作者信息
Doi O, Miyamoto M, Tanaka N, Umezawa H
出版信息
Appl Microbiol. 1968 Sep;16(9):1282-4. doi: 10.1128/am.16.9.1282-1284.1968.
Abstract
The cell-free system of clinical isolates of drug-resistant Staphylococcus aureus inactivated kanamycin, and the inactivated product was identified with kanamycin-3'-phosphate, in which the C-3-OH of the 6-amino-6-deoxy-d-glucose moiety of kanamycin was phosphorylated.
摘要
耐甲氧西林金黄色葡萄球菌临床分离株的无细胞系统可使卡那霉素失活，失活产物经鉴定为3'-磷酸卡那霉素，其中卡那霉素6-氨基-6-脱氧-d-葡萄糖部分的C-3-OH被磷酸化。
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