二（2-羟丙基）亚硝胺（DHPN）对雄性Wistar大鼠的致癌作用：生大豆粉饮食对胰腺癌的促进作用。
Carcinogenic effects of Di(2-hydroxypropyl)nitrosamine (DHPN) in male Wistar rats: promotion of pancreatic cancer by a raw soya flour diet.
作者信息
Levison D A, Morgan R G, Brimacombe J S, Hopwood D, Coghill G, Wormsley K G
出版信息
Scand J Gastroenterol. 1979;14(2):217-24. doi: 10.3109/00365527909179873.
PMID:571138
Abstract
Di(2-hydroxypropyl)nitrosamine was administered to rats fed raw or heated (control) soya flour diets. The group fed raw soya flour developed hyperplastic and adenomatous pancreatic nodules and pancreatic adenocarcinomata. We conclude that a diet of raw soya flour augments the carcinogenicity of pancreatic carcinogens in the rat.
摘要
将二（2-羟丙基）亚硝胺给予喂食生大豆粉或加热（对照）大豆粉饮食的大鼠。喂食生大豆粉的组出现了增生性和腺瘤性胰腺结节以及胰腺腺癌。我们得出结论，生大豆粉饮食会增强大鼠胰腺致癌物的致癌性。
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