虫媒病毒指导的蛋白质合成
Protein synthesis directed by an arbovirus.
作者信息
Friedman R M
出版信息
J Virol. 1968 Jan;2(1):26-32. doi: 10.1128/JVI.2.1.26-32.1968.
Abstract
In contrast to chick embryo fibroblast protein synthesis, the bulk of the protein synthesis directed by Semliki Forest virus is carried out on membranes. Under conditions where more than 95% of cell protein synthesis was inhibited, viral polysomes could be demonstrated. Viral protein appeared to be produced on polysomes associated with nascent ribonucleic acid strands still attached to the base-paired, double-stranded replicative form of the virus. Very rapid incorporation of virus protein into 140S virus core particles was also demonstrated.
摘要
与鸡胚成纤维细胞的蛋白质合成不同，辛德毕斯病毒指导的大部分蛋白质合成是在膜上进行的。在超过95%的细胞蛋白质合成受到抑制的条件下，可以证明病毒多核糖体的存在。病毒蛋白似乎是在与仍附着于病毒碱基配对双链复制形式的新生核糖核酸链相关的多核糖体上产生的。还证明了病毒蛋白能非常迅速地掺入140S病毒核心颗粒中。
相似文献
1
Protein synthesis directed by an arbovirus.虫媒病毒指导的蛋白质合成
J Virol. 1968 Jan;2(1):26-32. doi: 10.1128/JVI.2.1.26-32.1968.
2
3
Interferon action on parental Semliki forest virus ribonucleic acid.干扰素对亲本塞姆利基森林病毒核糖核酸的作用。
J Virol. 1967 Dec;1(6):1168-73. doi: 10.1128/JVI.1.6.1168-1173.1967.
4
Optimization of the interferon assay using inhibition of Semliki forest virus-ribonucleic acid synthesis.利用塞姆利基森林病毒核糖核酸合成抑制优化干扰素测定法。
Appl Microbiol. 1972 Sep;24(3):323-7. doi: 10.1128/am.24.3.323-327.1972.
5
Studies on the synthesis of viral RNA-polymerase-template complexes in BHK 21 cells infected with Semliki Forest virus.
Virology. 1975 Jul;66(1):322-6. doi: 10.1016/0042-6822(75)90202-0.
6
Inhibition of interferon action by puromycin.嘌呤霉素对干扰素作用的抑制
J Immunol. 1965 Oct;95(4):696-703.
7
Isolation and basic characterization of temperature-sensitive mutants from Semliki Forest virus;从塞姆利基森林病毒中分离温度敏感突变体并进行基本特性分析；
Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Dec;82(6):810-20. doi: 10.1111/j.1699-0463.1974.tb02378.x.
8
Inhibition of arbovirus protein synthesis by interferon.干扰素对虫媒病毒蛋白质合成的抑制作用。
J Virol. 1968 Oct;2(10):1081-5. doi: 10.1128/JVI.2.10.1081-1085.1968.
9
Stability and precursor relationships of virus RNA.病毒RNA的稳定性及前体关系
J Gen Virol. 1972 Nov;17(2):213-9. doi: 10.1099/0022-1317-17-2-213.
10
STUDIES ON THE MECHANISM OF ACTION OF INTERFERON. I. INTERFERON ACTION AND RNA SYNTHESIS IN CHICK EMBRYO FIBROBLASTS INFECTED WITH SEMLIKI FOREST VIRUS.干扰素作用机制的研究。I. 感染辛德毕斯病毒的鸡胚成纤维细胞中的干扰素作用与RNA合成
Virology. 1965 Mar;25:340-9. doi: 10.1016/0042-6822(65)90053-x.
引用本文的文献
1
Inhibition of arbovirus assembly by cycloheximide.放线菌酮对虫媒病毒装配的抑制作用。
J Virol. 1969 Sep;4(3):292-9. doi: 10.1128/JVI.4.3.292-299.1969.
2
Morphogenesis of aura virus.奥拉病毒的形态发生
J Virol. 1969 Sep;4(3):271-82. doi: 10.1128/JVI.4.3.271-282.1969.
3
Electron microscopic studies of bovine viral diarrhea virus in tissues of diseased calves and in cell cultures.对患病犊牛组织和细胞培养物中牛病毒性腹泻病毒的电子显微镜研究。
Arch Virol. 1982;71(1):57-74. doi: 10.1007/BF01315175.
4
Kinetics of incorporation of structural proteins into Sindbis virions.结构蛋白掺入辛德毕斯病毒粒子的动力学
J Virol. 1969 Apr;3(4):369-75. doi: 10.1128/JVI.3.4.369-375.1969.
5
Cytoplasmic structures associated with an arbovirus infection: loci of viral ribonucleic acid synthesis.与虫媒病毒感染相关的细胞质结构：病毒核糖核酸合成位点。
J Virol. 1968 Nov;2(11):1326-38. doi: 10.1128/JVI.2.11.1326-1338.1968.
6
Replicative intermediate of an arbovirus.虫媒病毒的复制中间体。
J Virol. 1968 Jun;2(6):547-52. doi: 10.1128/JVI.2.6.547-552.1968.
7
Structural and nonstructural proteins of an arbovirus.一种虫媒病毒的结构蛋白和非结构蛋白。
J Virol. 1968 Oct;2(10):1076-80. doi: 10.1128/JVI.2.10.1076-1080.1968.
8
Lack of oncogenic potential of measles virus on Syrian hamster embryo cell cultures.麻疹病毒对叙利亚仓鼠胚胎细胞培养物无致癌潜力。
J Virol. 1968 May;2(5):543-4. doi: 10.1128/JVI.2.5.543-544.1968.
9
Influence of an arbovirus infection (Sindbis virus) on the protein and ribonucleic acid synthesis of cultivated chick embryo cells.一种虫媒病毒感染（辛德毕斯病毒）对培养的鸡胚细胞蛋白质和核糖核酸合成的影响。
Arch Gesamte Virusforsch. 1970;31(1):81-92. doi: 10.1007/BF01241668.
10
Host effect on arbovirus replication: appearance of defective interfering particles in murine cells.宿主对虫媒病毒复制的影响：小鼠细胞中缺陷干扰颗粒的出现。
J Virol. 1973 Dec;12(6):1401-6. doi: 10.1128/JVI.12.6.1401-1406.1973.
本文引用的文献
1
Electron Microscope Studies of Ribosomal Clusters Synthesizing Hemoglobin.合成血红蛋白的核糖体簇的电子显微镜研究
Science. 1962 Dec 28;138(3548):1399-403. doi: 10.1126/science.138.3548.1399.
2
The cytoplasmic synthesis of histones in hela cells and its temporal relationship to DNA replication.海拉细胞中组蛋白的细胞质合成及其与DNA复制的时间关系。
Proc Natl Acad Sci U S A. 1967 Feb;57(2):409-16. doi: 10.1073/pnas.57.2.409.
3
POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA.正常及脊髓灰质炎病毒感染的海拉细胞中的多核糖体及其与信使核糖核酸的关系
Proc Natl Acad Sci U S A. 1963 May;49(5):654-62. doi: 10.1073/pnas.49.5.654.
4
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
5
Effect of p-fluorophenylalanine and puromycin on the replication of poliovirus.对氟苯丙氨酸和嘌呤霉素对脊髓灰质炎病毒复制的影响。
Virology. 1962 Mar;16:220-9. doi: 10.1016/0042-6822(62)90241-6.
6
STUDIES ON THE MECHANISM OF ACTION OF INTERFERON. I. INTERFERON ACTION AND RNA SYNTHESIS IN CHICK EMBRYO FIBROBLASTS INFECTED WITH SEMLIKI FOREST VIRUS.干扰素作用机制的研究。I. 感染辛德毕斯病毒的鸡胚成纤维细胞中的干扰素作用与RNA合成
Virology. 1965 Mar;25:340-9. doi: 10.1016/0042-6822(65)90053-x.
7
THE IN VITRO FORMATION OF A DNA-RIBOSOME COMPLEX.DNA-核糖体复合物的体外形成
Proc Natl Acad Sci U S A. 1964 Jul;52(1):140-8. doi: 10.1073/pnas.52.1.140.
8
Replication of Semliki Forest virus: an electron microscopic study.Semliki森林病毒的复制：一项电子显微镜研究。
Virology. 1967 May;32(1):128-43. doi: 10.1016/0042-6822(67)90261-9.
9
The effect of interferon on the synthesis of RNA in chick cells infected with Semliki forest virus.干扰素对感染辛德毕斯病毒的鸡细胞中RNA合成的影响。
J Gen Virol. 1967 Jan;1(1):25-40. doi: 10.1099/0022-1317-1-1-25.
10
Changes in morphology, infectivity and haemagglutinating activity of Semliki Forest virus produced by the treatment with caseinase C from Streptomyces albus G.用来自白色链霉菌G的酪蛋白酶C处理产生的Semliki森林病毒在形态、感染性和血凝活性方面的变化。
J Gen Microbiol. 1966 Apr;43(1):19-30. doi: 10.1099/00221287-43-1-19.
Zotero 插件